N/A
Completed N=12
Legume Diet Satiety Pilot Study
Source: ClinicalTrials.gov NCT02269631 ↗Enrolled (actual)
12
Serious AEs
0.0%
Results posted
Jan 2019
Primary outcomePrimary: Change in Weight — 9.2; 6.6 lbs
Summary
This pilot study is designed to test the effects of a high legume (dried bean) diet on hunger and other indicators of health over the course of eight weeks, compared to a more conventional healthy diet.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Weight |
9.2; 6.6 | — |
| SECONDARY Gastric Emptying Time |
25.8; 53.8 | — |
| SECONDARY Change in Plasma Insulin Level (Biomarker of Appetite Regulation) |
-9.9; 5.9 | — |
| SECONDARY Energy Intake |
— | — |
| SECONDARY Satiety |
— | — |
Eligibility Criteria
Inclusion Criteria
- BMI overweight-obese: 25.0-40 kg/m2
- Colonoscopy within the last two years that found ≥1 adenoma
- English speaking
- Ambulatory, able to come to either food distribution site to pick up food and participate in clinical examinations and laboratory tests
Exclusion Criteria
- Serious medical condition (e.g., cancer, heart disease, kidney disease, diabetes)
- History of CRC, bowel resection, polyposis syndrome, or inflammatory bowel disease
- Smoked regularly in the past year
- Dietary restrictions substantially limiting compliance or vegetarian or Vegan diet
- Planning on changing diet or exercise behavior in the next 6 months
- Regular use of medication that may alter inflammation markers, insulin, glucose, or gut function (i.e. regular use of non-steroidal anti-inflammatory medication, insulin therapy, steroid therapy, or antibiotics)
Data sourced from ClinicalTrials.gov (NCT02269631). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.