N/A
Completed N=17
Evaluating the Influence of Apnea on Cardiac Function Using Cardiac Magnetic Resonance Imaging.
Physiological Changes in Deliberate Apnea
Source: ClinicalTrials.gov NCT02280226 ↗
Enrolled (actual)
17
Serious AEs
—
Results posted
Feb 2018
Primary outcomePrimary: Cardiac Function: Duration of Apnea — 483 sec
Summary
Former studies revealed a distinct pattern of changes in circulation during deliberate apnea. Blood pressure rises significantly often accompanied by bradycardia. Further studies confirmed a massive increase of total vascular resistance as it also happens in shock to maintain perfusion of heart, lung and brain. This study is to determine the exact alterations of the cardiac function during this reaction, show the redistribution of blood volume in apnea and evaluate possible longterm effects on the central nervous system caused by repeated apnea via magnetic resonance imaging.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Cardiac Function: Duration of Apnea |
483 | — |
| PRIMARY Mean Blood Flow Measurement Under Apnea Using MRI |
82 | — |
Eligibility Criteria
Inclusion Criteria
- Being able to hold breath deliberately at least 4,5 minutes
Exclusion Criteria
-
Data sourced from ClinicalTrials.gov (NCT02280226). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.