N/A N=14

Examining Endogenous Antioxidant Levels in Well Trained Cyclists

Oxidative Stress

Bottom Line

View on ClinicalTrials.gov: NCT02281851 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Apr 2020

Primary outcome: Primary: Difference in Resting Levels of Endogenous Antioxidant Proteins in Skeletal Muscle - Superoxide Dismutase 2 (SOD-2) — 0.42; 0.68 Arbitrary Units

Study Design & Population

Study type: Observational
Phase: N/A
Interventions: —
Age: Adult · 18+ yrs
Sex: Male
Sponsor: University of Birmingham
Primary completion: May 2016

Outcome Measures

Outcome	Result	p-value
PRIMARY Difference in Resting Levels of Endogenous Antioxidant Proteins in Skeletal Muscle - Superoxide Dismutase 2 (SOD-2)	0.42; 0.68	—

Summary

This study will investigate whether increased habitual intake of antioxidant supplements effects the concentration of endogenous antioxidants, the response of antioxidants to exercise, and differences in oxidative damage compared to a non-supplemented group.

Eligibility Criteria

Inclusion Criteria

Male,
BMI 18.8 29.9 kg/m2
cycle 3-7 times a week for durations longer than 60 minutes
cycled for a minimum of 3 years
accustomed to exhaustive cycling protocols
healthy (no known cardiovascular or metabolic disease)

Exclusion Criteria

answering "NO" to any question on the general health questionnaire would result in exclusion from the study
current participation in another clinical study
current or recent smoker (last 30 days)
prescription or non-prescription of anti-inflammatory use >30 days prior to the experiment commencing or any other medications that in the opinion of the investigator may interfere with redox signalling

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02281851). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.