N/A
N=166
The Validity, Reliability and Interpretability of Thai-version of Chronic Urticaria Quality of Life Questionnaire
Chronic Urticaria
Bottom Line
View on ClinicalTrials.gov: NCT02285023 ↗Enrolled (actual)
166
Serious AEs
0.0%
Results posted
Feb 2019
Primary outcome: Primary: Cross-Cultural Validity of Thai-version CU-Q2oL — 43.71; 22.11; 9.41; 20.21 Percentage — p=<0.01
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- CU-Q2oL (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Mahidol University
- Primary completion
- Feb 2015
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Cross-Cultural Validity of Thai-version CU-Q2oL |
43.71; 22.11; 9.41; 20.21; 7.33; 18.13 | <0.01 sig |
| SECONDARY Mean Total Score and Domain of Thai CU-Q2oL Scores From the Thai Version to Investigate Reliability of Thai-Version CU-Q2oL |
23.19; 1.86; 19.09; 1.79; 18.37; 1.85 | <0.05 sig |
| SECONDARY Change in Thai CU-Q2oL Scores From Baseline for Responders and Non-Responders |
7.3; 28.4 | — |
| SECONDARY Area Under the Curve for Thai CUQ2oL Scores in the Responder Group |
0.90 | — |
Summary
In the majority of patients with the chronic urticaria, the etiology is unclear, leading to difficulties in treatment and high rates of recurrence. According to the International EAACI/GA2LEN/EDF/WAO Guidelines (the Dermatology Section of the European Academy of Allergology and Clinical Immunology(EAACI), the Global Allergy and Asthma European Network (GA2LEN), the European Dermatology Forum (EDF) and the World Allergy Organization (WAO) in Urticaria, using the Chronic Urticaria Quality of Life Questionnaire in a routine management is the key for a better treatment outcome. To translate this questionnaire into Thai is essential in our subject of interest in order to effectively apply it to local patients. The Thai-version questionnaire will encourage enhanced as well as impactful therapeutic options for Thai chronic urticaria patients.
Eligibility Criteria
Inclusion Criteria
- Age 18 years old or above
- Diagnosed as chronic urticaria based on "The EAACI/GA(2)LEN/EDF/WAO Guideline
- Literate in Thai language and can complete the questionnaire by themselves
Exclusion Criteria
- Have other active skin diseases
- Have a psychiatric problem
- Cannot understand the questionnaire by themselves.
Data sourced from ClinicalTrials.gov (NCT02285023). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.