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N/A N=475 Randomized Other

Effectiveness of Two Silicone Dressings for Sacral and Heel Pressure Ulcer Prevention

Pressure Ulcer

Enrolled (actual)
475
Serious AEs
0.0%
Results posted
Jul 2020
Primary outcome: Primary: Number of Pressure Ulcers Category II, III, IV, Unstageable, Deep Tissue Injury (DTI) at Heels and/or Sacrum (Proportion) — 6; 22 Pressure ulcer

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Mepilex® Border Sacrum and Mepilex® Border Heel (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
PD Dr. Jan Kottner
Primary completion
Jul 2018

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Pressure Ulcers Category II, III, IV, Unstageable, Deep Tissue Injury (DTI) at Heels and/or Sacrum (Proportion)
6; 22
SECONDARY
Density Rate of Pressure Ulcers Category II, III, IV, Unstageable, Deep Tissue Injury (DTI) at Heels and/or Sacrum (Proportion Per 1000 Bed Days, Rate)
7.8; 30.5
SECONDARY
Number of Pressure Ulcer Category I (Non-blanchable Erythema) II, III, IV, Unstageable, Deep Tissue Injury (DTI) at Heels and/or Sacrum (Proportion)
6; 28
SECONDARY
Number of Pressure Ulcers Category I (Non-blanchable Erythema) II, III, IV, Unstageable, Deep Tissue Injury (DTI) at Heels and/or Sacrum (Proportion Per 1000 Bed Days, Rate)
8.0; 37.6
SECONDARY
Number of Preventive Sacrum Dressings Used for Pressure Ulcer Prevention
1050; 0
SECONDARY
Numbers of Support Surface Used for Pressure Ulcer Prevention (Total)
212; 209; 149; 117; 79; 85
SECONDARY
Time to Pressure Ulcer Development of Pressure Ulcers Category II, III, IV, Unstageable, Deep Tissue Injury (DTI) at Heels and/or Sacrum
10.8; 13.5
SECONDARY
Number of Preventive Heel Dressings Used for Pressure Ulcer Prevention
2260; 0
SECONDARY
Time to Pressure Ulcer Development of Pressure Ulcers Category I, II, III, IV, Unstageable, Deep Tissue Injury (DTI) at Heels and/or Sacrum
10.8; 13.2
SECONDARY
Event Free Survival Time of Pressure Ulcers Category II, III, IV, Unstageable, Deep Tissue Injury (DTI) at Heels and/or Sacrum (Days, Kaplan Meier Analysis)
60.7; 89.0
SECONDARY
Event Free Survival Time of Pressure Ulcers Category I, II, III, IV, Unstageable, Deep Tissue Injury (DTI) at Heels and/or Sacrum (Days, Kaplan Meier Analysis)
60.7; 54.6
SECONDARY
Follow up Period of Included ICU Patients (Days)
11.0; 14.3

Summary

The aim of this randomized controlled trial is to test the efficacy of preventive dressings for pressure ulcer prevention.

Eligibility Criteria

  • Major trauma patients and/or critically ill patients (e.g. with cardiac arrest) admitted to the emergency department and being transferred and/or admitted directly to a surgical or internal ICU
  • Being at "high" or "very high" PU risk according to the Charité PU prevention standard:
  • Category 3 (= partly care dependent/limited mobility in bed), 4A (= care depended, limited mobility in bed), 4B (= totally immobile) according to the Jones classification modified by Charité
  • Expected minimum length of stay at least three days
  • Informed consent (or by legal representative)
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02295735). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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