N/A
N=439
Comparison of DSM-IV-TR and DSM-5 for ASD
Autism Spectrum Disorder
Bottom Line
View on ClinicalTrials.gov: NCT02296502 ↗Enrolled (actual)
439
Serious AEs
0.0%
Results posted
Mar 2019
Primary outcome: Primary: Clinical Features of Concordant vs Discordant Groups — 76.18; 89.85; 14.96; 13.94 units on a scale
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- DSM (Other)
- Age
- Pediatric · 2+ yrs
- Sex
- All
- Sponsor
- University of Pittsburgh
- Primary completion
- Nov 2016
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Clinical Features of Concordant vs Discordant Groups |
76.18; 89.85; 14.96; 13.94; 12.83; 8.22 | — |
| PRIMARY Sensitivity and Specificity of DSM-5 Criteria for ASD Relative to DSM-IV Criteria |
0.25; 0.80; 0.97; 0.89; 0.89; 0.41 | — |
Summary
The study aim is to prospectively compare DSM-IV-TR and DSM-5 criteria for Autism Spectrum Disorder (ASD) in a sample of 250 children and adolescents who meet DSM-IV-TR criteria for ASD and 150 children and adolescents referred for diagnosis who do not meet DSM-IV-TR criteria.Families and children will be recruited from eight sites affiliated with the Autism Treatment Network (ATN). Participants must be between the ages of 2.0 and 17.11 years who undergo an ATN assessment at one of the eight sites. Both subjects who are found to meet criteria of ASD/PDD and those who do not meet criteria (after completing the ATN assessment) will be enrolled. After completing the standard ATN assessment, clinicians will complete a DSM-IV and DSM-5 checklist for ASD/PDD.
Eligibility Criteria
Inclusion Criteria
- age 2-17
- question of possible autism spectrum disorder
Exclusion Criteria
- 17 years old
Data sourced from ClinicalTrials.gov (NCT02296502). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.