Sensory severity predicts insula decoupling in autistic participants during motion stimulation
Sensory severity in autism forms a continuous pattern, not distinct categories
This cohort study examined 223 behavioral participants and 63 neurobiological participants with autism spectrum disorder. Sensory severity p…
New data show sensory processing differences in autism are a continuous spectrum rather than separate types, changing how we understand thes…
Neuroimaging features predict ASD identification and cognitive decoding accuracy in large cohorts
New AI Model Finds Brain Pattern That Predicts Autism Symptoms
This cohort study analyzed individuals from three independent large-scale neuroimaging cohorts (HCP-task, ABIDE-I, ABIDE-II). Cognitive deco…
A new tool finds a clear brain signal that predicts autism symptoms with high accuracy.
Review of human postmortem studies finds region-dependent microglial variation in autism spectrum disorder brains
Brain scans show microglia vary by region and stage in autism
This review analyzed human postmortem studies using bulk transcriptomics and single-cell atlases to examine microglia in autism spectrum dis…
A review of brain tissue suggests immune cells in autism differ by location and development rather than showing one single pattern across al…
ADHD and ASD polygenic risk scores correlate with antipsychotic responsiveness in schizophrenia postmortem brains
Genes for ADHD and Autism May Predict Schizophrenia Drug Response
This postmortem brain study in 24 patients with schizophrenia and 48 controls examined polygenic risk scores for ADHD and ASD. It found a su…
Genes tied to ADHD and autism may predict how well antipsychotic drugs work in schizophrenia patients.
Children with autism lack auditory looming bias seen in typical development
Brain scans show autistic kids hear approaching sounds differently
This primary trial compared EEG responses to looming vs receding sounds in 3-4-year-old children with autism, sensory concerns, or typical d…
Brain scans reveal preschoolers with autism process approaching sounds differently than typical children do, pointing to unique sensory wiri…
Genetic study of autism in African Americans shows limited transferability of European-derived polygenic scores
Autism genes differ by ancestry—new clues in Black families
This cohort study of 38,483 autistic individuals compared genetic findings between African and European ancestries. Common variant effects w…
Black children with autism carry different genetic clues than white children, a landmark study shows—meaning better answers and fairer care …
Review of vagus nerve stimulation for autism spectrum disorder and maternal immune activation
Vagus nerve stimulation shows promise for autism and maternal immune activation
This narrative review examines vagus nerve stimulation (VNS) in the context of autism spectrum disorder and maternal immune activation. The …
A review suggests vagus nerve stimulation could help people with autism spectrum disorder or those affected by maternal immune activation.
Review of serotonergic signaling in autism spectrum disorder and other neurodevelopmental conditions
Serotonin’s Hidden Role in Brain Development Depends on Sex
This narrative review examines the role of serotonergic signaling in autism spectrum disorder and other psychiatric and neurodevelopmental c…
This discovery may help explain why conditions like autism affect boys and girls so differently.
Systematic review links CNTN6 gene to neurodevelopmental and mental disorders
This Brain Protein Might Explain Autism and Schizophrenia
This systematic review summarizes evidence on CNTN6 gene involvement in neurodevelopment and disease. Rodent studies show CNTN6 protein affe…
Scientists have identified a specific protein that helps wire the brain and may be linked to mental health conditions.
Protocol for Global Integration Method in children with ASD aged 6 to 12 years
New Therapy Targets Motor Skills in Children With Autism
This randomized controlled trial protocol evaluates the Global Integration Method (Método de Integração Global - MIG) versus conventional ps…
This research could help children with autism move more freely and confidently in their daily lives.
Atypical absences linked to higher autistic behavior scores in SYNGAP1-DEE patients
Seizure Type Predicts Autism Severity Better Than Frequency Does
This observational cohort study of 337 patients with SYNGAP1-related developmental and epileptic encephalopathy found that atypical absences…
For children with this rare condition, the kind of seizure matters more for autism symptoms than how often they occur.
Narrative review examines antioxidant metabolites for autism spectrum disorder in children
Could antioxidant nutrients help children with autism spectrum disorder?
This narrative review evaluates the potential role of antioxidant metabolites from botanical drugs and nutrients, including vitamins E and C…
Antioxidant nutrients like vitamins E and C, plus botanical compounds, may help address oxidative stress linked to autism spectrum disorder …