Phase 2 N=50 Randomized Triple-blind Treatment

Bicarbonate in Patients With Out-of-hospital Cardiac Arrest

Cardiac Arrest · Metabolic Acidosis

Bottom Line

View on ClinicalTrials.gov: NCT02303548 ↗

Enrolled (actual)

Serious AEs

98.0%

Results posted

Jul 2019

Primary outcome: Primary: Return of Spontaneous Circulation (ROSC) — 4; 16 ROSC percents of each group

Study Design & Population

Study type: Interventional
Phase: Phase 2
Interventions: Sodium bicarbonate (Drug); Normal saline (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Asan Medical Center
Primary completion: Feb 2016

Outcome Measures

Outcome	Result	p-value
PRIMARY Return of Spontaneous Circulation (ROSC)	4; 16	—

Summary

A pilot study to evaluate the effect of sodium bicarbonate administration on cardiopulmonary resuscitation results and outcomes in cardiac arrest patient with severe metabolic acidosis.

Eligibility Criteria

Inclusion Criteria

adult cardiac arrest patient with arterial pH <7.1 or bicarbonate <10mmEq/L checked at 10 minutes of cardiopulmonary resuscitation

Exclusion Criteria

age <18 trauma patient Do Not Resuscitate state

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02303548). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.