N/A
N=36
Treatment Intensity - Apraxia of Speech
Aphasia · CVA · Apraxia of Speech
Bottom Line
View on ClinicalTrials.gov: NCT02332915 ↗Enrolled (actual)
36
Serious AEs
0.0%
Results posted
Nov 2020
Primary outcome: Primary: Accuracy of Articulation of TREATED ITEMS Measured as Effect Size - Change From Baseline to End of Treatment Phase — 19.7; 28.9 effect sizes; magnitude of change — p=.0128
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Sound Production Treatment (SPT) (Behavioral)
- Age
- Adult, Older Adult · 21+ yrs
- Sex
- All
- Sponsor
- VA Office of Research and Development
- Primary completion
- Oct 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Accuracy of Articulation of TREATED ITEMS Measured as Effect Size - Change From Baseline to End of Treatment Phase |
19.7; 28.9 | .0128 sig |
| PRIMARY Accuracy of Articulation of Untreated Items (Generalization) Measured as Effect Size - Change From Baseline to End of Treatment Phase |
7.9; 8.1 | .942 |
| SECONDARY Speech Intelligibility - Percent Intelligible Words Comparing Baseline to End of Treatment Phases |
45.15; 46.15; 48.96; 54.3; 61.5; 60.5 | <.001 sig |
Summary
A growing neurorehabilitation literature suggests that intense treatment may be desired to maximize the effects of therapy following neurologic injury. This investigation is designed to facilitate the development of efficacious, clinically applicable treatment for acquired apraxia of speech by examining the effects of intensity of treatment (e.g., 9 hours per week vs. 3 hours per week, while holding total number of sessions constant) with a group of speakers who have chronic apraxia of speech and aphasia.
Eligibility Criteria
Inclusion Criteria
- Veterans and non Veterans
- Males or females
- Stroke survivor who is at least 4 months post-stroke
- Speaker of English since childhood
- Ability to pass a pure-tone hearing screening (aided or unaided)
- currently non-hospitalized
- Age 21 to 90 years
Exclusion Criteria
- neurological condition other than stroke
- currently clinically depressed
- history of speech/language problems prior to stroke
- untreated psychopathology
Data sourced from ClinicalTrials.gov (NCT02332915). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.