N/A
Completed N=20
Chest Pain Perception and Capsaicin Sensitivity in Patients With Acute Cardiac Ischemia
Source: ClinicalTrials.gov NCT02346916 ↗Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Mar 2021
Primary outcomePrimary: Capsaicin Sensitivity — 2.05 score on a scale
Summary
The purpose of this study is to determine whether there is a positive correlation between the ability to sense chest pain in the context of myocardial ischemia and the ability to sense discomfort associated with the topical application of the TRPV1 agonist capsaicin (the active ingredient on hot chili peppers).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Capsaicin Sensitivity |
2.05 | — |
| SECONDARY Chest Pain |
2.50 | — |
Eligibility Criteria
Inclusion Criteria
Subjects will consist of patients who have undergone clinically-indicated PCI for the treatment of coronary artery disease. This study will include clinically unstable patients, such as those undergoing emergency percutaneous coronary intervention (PCI) for acute myocardial infarction, etc.
Exclusion Criteria
Patients with documented hypersensitivity to capsaicin will be excluded and patients who have used a capsaicin-based product within the last 3 months will be excluded
Data sourced from ClinicalTrials.gov (NCT02346916). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.