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N/A N=30

Single-centre, Registry Trial, the Patients Presented With Stable Coronary Artery Disease

Coronary Artery Disease

Enrolled (actual)
30
Serious AEs
Results posted
Jul 2016
Primary outcome: Primary: MLD SB Diameter — 08.; 1.0; 2.3; 2.2 mm

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Icahn School of Medicine at Mount Sinai
Primary completion
May 2015

Outcome Measures

OutcomeResultp-value
PRIMARY
MLD SB Diameter
08.; 1.0; 2.3; 2.2
SECONDARY
SB Angle
140.3; 147.7; 140.5; 141.5; 48.0; 49.9
SECONDARY
SB Ostial Involvement
1.4; 1.6; 0.8; 1.8
SECONDARY
Diameter Stenosis (DS)
30.0; 24.0; 63.1; 27.7

Summary

This is a prospective study to analyze the outcome of provisional main vessel stenting on side branch by utilizing Two-Dimensional (2D) and Three-Dimensional (3D) frequency domain optical coherence tomography (FD-OCT). To analyze the fate of side-branch after provisional main vessel stenting based on morphology defined prior to PCI by OCT. Offline analysis of side branch impingement of the ostium of SB leading to acute loss in SB diameter area, carina shift and plaque shift will be also be performed.

Eligibility Criteria

Inclusion Criteria

  • Over 18 years of age presenting with stable coronary artery disease.
  • Angiographic lesion not involving side branch (SB) in whom provisional main vessel stenting strategy is planned after reviewing angiogram will be recruited

Exclusion Criteria

  • Patient with lesion involving side branch ( >70 %) by angiogram and need pre-dilation.
  • Patients with ostial left main artery lesions or ostial right coronary artery lesions
  • Female patients with child bearing potential not taking adequate contraceptives or currently breastfeeding
  • Known allergy to acetylsalicylic acid or clopidogrel.
  • Planned surgery within 12 months.
  • History of bleeding diathesis
  • Major surgery within 15 days
  • Life expectancy < 12 months.
  • Patients with kidney dysfunction (CrCl<30)
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02364778). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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