N/A Completed N=150 Randomized Single-blind Treatment

Dietary Carbohydrate and GERD in Veterans

Gastroesophageal Reflux Disease · Obesity

Source: ClinicalTrials.gov NCT02384551 ↗

Enrolled (actual)

150

Serious AEs

0.7%

Results posted

Sep 2024

Primary outcomePrimary: Gastroesophageal pH — 7.3; 6.6; 3.7; 4.9 percent time ph < 4 in 24 hrs

Summary

4-Arm Diet Intervention Investigating Effects of Dietary Carbohydrate Type and Amount on gastroesophageal pH, gastroesophageal reflux disease (GERD) symptoms and medication use.

Outcome Measures

Outcome	Result	p-value
PRIMARY Gastroesophageal pH	7.3; 6.6; 3.7; 4.9	—
SECONDARY Gastroesophageal Reflux Disease Questionnaire (GERDQ) Score	5.1; 3.2; 4.5; 3.5	—
SECONDARY Gastroesophageal Scale Assessment Symptom (GSAS) Score	5.6; 4.1; 5.6; 4.5	—

Eligibility Criteria

Inclusion Criteria

Age 21 or over BMI 30-39.9 GERD

Exclusion Criteria

History of type 1 diabetes
Hernia or strictures
Gastroparesis
Extra-esophageal GERD
Barrett's esophagus or Esophageal adenocarcinoma
History of gastric or bariatric or esophageal surgery, radiation or cancer
History of gastrointestinal malabsorption
Alcohol averaging > 2 drinks per day during past 3 months
Pregnancy / Lactation

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02384551). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.