N/A
N=18
Renal Perfusion, Filtration and Oxygenation During Cardiopulmonary Bypass (CPB)
Complication of Extracorporeal Circulation · Renal Impairment
Bottom Line
View on ClinicalTrials.gov: NCT02405195 ↗Enrolled (actual)
18
Serious AEs
0.0%
Results posted
May 2019
Primary outcome: Primary: Renal Blood Flow (RBF) — 554; 524; 564; 558 ml per minute per 1.73 m2 body surface — p=0.638
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- cardiopulmonary bypass (Procedure)
- Age
- Adult, Older Adult · 19+ yrs
- Sex
- All
- Sponsor
- Sahlgrenska University Hospital
- Primary completion
- Dec 2015
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Renal Blood Flow (RBF) |
554; 524; 564; 558 | 0.638 |
| PRIMARY Glomerular Filtration Rate (GFR) |
67; 68; 70; 67 | 0.972 |
| PRIMARY Renal Oxygenation |
0.09; 0.12; 0.13; 0.16 | <0.001 sig |
| SECONDARY Excretion of NAG |
— | — |
| SECONDARY Development of Acute Kidney Injury (AKI) |
— | — |
Summary
Acute kidney injury is a common complication after cardiac surgery with cardiopulmonary bypass (CPB). This study aims to investigate the effects of CPB on renal perfusion, filtration and oxygenation.
Eligibility Criteria
Inclusion Criteria
- Preserved left ventricular function (LVEF > 50%)
- Normal preoperative S-creatinine
Exclusion Criteria
- Contraindications to radiocontrast
- Cardiac transplantation och dissection
Data sourced from ClinicalTrials.gov (NCT02405195). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.