Model-informed precision dosing improves vancomycin target attainment in critically ill children compared to standard therapeutic drug monitoring
New dosing model helps severely ill children hit drug targets faster
In critically ill children, model-informed precision dosing significantly improved vancomycin target attainment versus standard monitoring. …
A new dosing method helped more critically ill children reach the right drug levels in their blood within two days of starting treatment for…
Narrative review offers theoretical basis for selecting biologic therapies in psoriasis patients with renal concerns
New Psoriasis Treatments May Protect Kidneys While Fighting Skin Flares
This narrative review examines the use of TNF-alpha, IL-17, and IL-12/23 inhibitors in psoriasis patients with renal concerns. The authors p…
• Some biologics shield kidneys from damage during psoriasis treatment • Helps the 8 million Americans with psoriasis and kidney worries • N…
Tenofovir Disoproxil Fumarate in Maternal ART Linked to Modest Creatinine Decline in HIV-Positive Women
Women on TDF-based HIV meds showed kidney changes compared to infant-only treatment
This randomized trial compared tenofovir disoproxil fumarate (TDF)-containing maternal antiretroviral therapy (ART) with infant nevirapine p…
Women taking TDF-based HIV meds had larger drops in kidney function than those on infant-only treatment, but calcium and phosphate levels st…
Research across Kidney Diseases
Related studies from across the Kidney Diseases family.
Environmental cadmium exposure may cause male reproductive dysfunction through the renal-testis axis
Cadmium exposure may harm male fertility and kidney health
This narrative review of 40 animal studies synthesizes evidence on environmental cadmium exposure and its impact on male reproduction. The a…
Environmental cadmium exposure can damage the male reproductive system and kidneys, potentially leading to lower semen quality and other iss…
Programmed cell death pathways form a spatiotemporally regulated network driving tubular damage in renal IRI
New research identifies key pathways driving acute kidney injury
This systematic review examines the roles of pyroptosis, ferroptosis, cuproptosis, and necroptosis as key mediators of inflammation and oxid…
Researchers have mapped out a complex network of cell death pathways that drive inflammation and damage in patients with acute kidney injury…
Fluoroless ultrasound-guided techniques lower complications in percutaneous nephrolithotomy with equivalent stone-free rates
Fluoroless ultrasound guidance reduces complications during kidney stone surgery
This systematic review and meta-analysis of randomized studies evaluated fluoroless ultrasound-guided versus fluoroscopy-guided techniques f…
A meta-analysis of randomized trials shows that using ultrasound instead of X-ray guidance lowers overall complications for kidney stone rem…
Meta-analysis of RCTs shows mPCNL yields higher single-session stone-free rates than RIRS for medium renal stones
Mini-PCNL clears kidney stones better than RIRS in one session
This meta-analysis of randomized controlled trials evaluated retrograde intrarenal surgery versus miniaturized percutaneous nephrolithotomy …
Mini-PCNL clears medium-sized kidney stones in one session more often than RIRS, but RIRS has fewer complications and shorter hospital stays…
Narrative review on anthracycline cardiorenal toxicity and dexrazoxane protection
Doctors seek better ways to protect heart and kidney health during cancer drug treatment
This narrative review synthesizes evidence on anthracycline-induced cardiorenal toxicity and dexrazoxane's protective role. The authors note…
Cancer treatments called anthracyclines can harm the heart and kidneys. This review explains why doctors need new strategies to keep patient…
Narrative review discusses exosomes for renal ischemia-reperfusion injury management and translational barriers
Tiny Kidney Protectors May Shield Patients From Sudden Damage
This narrative review examines the potential of exosomes for managing renal ischemia-reperfusion injury. The authors discuss the scope of th…
• Exosomes might prevent kidney harm when blood flow returns • Helps surgery patients and trauma survivors avoid kidney failure • Still in l…
Meta-analysis links suprarenal aortic repair techniques to higher risk of permanent renal dialysis in AAA patients
Large review shows kidney dialysis risk is higher when surgeons clamp above the kidney during aortic repair
This systematic review and meta-analysis evaluated the risk of permanent renal dialysis following various abdominal aortic aneurysm repair t…
A big study looked at over 72,000 patients having surgery for a bulging aorta. It found that operations touching the kidney area make kidney…
Narrative review on renal involvement in primary Sjögren's disease and therapeutic prospects
Understanding kidney problems in primary Sjogren's disease patients needs more research
This narrative review synthesizes current knowledge on renal involvement in primary Sjögren's disease. It highlights that the pathogenic bas…
Doctors are still learning how kidneys get hurt in primary Sjogren's disease. Current treatments work by guesswork because the exact cause i…
Patient-specific 3D printed kidney models improved comprehension and satisfaction compared to conventional 2D CT scans in PCNL patients
3D kidney models improve patient understanding before surgery
This randomized clinical study enrolled 40 individuals aged 18 to 80 planned for PCNL surgery.
A small study found that 3D printed kidney models significantly improved patient comprehension and satisfaction compared to standard 2D scan…
Surgical treatment for gouty tophi wounds associated with high healing rates in retrospective study
Surgery may help heal gouty tophi wounds
This retrospective cohort study of 130 patients with gouty tophi wounds in China observed high wound healing rates following surgical interv…
A small study shows that surgical treatment, including wound cleaning and vacuum drainage, helped most patients with gouty tophi wounds heal…
Retrospective cohort study links PPI use to drug-related problems in hospitalized renal disease patients
Nearly half of hospitalized kidney patients had drug problems linked to stomach acid reducers
This retrospective cohort study evaluated 520 hospitalized internal nephrology inpatients to assess drug-related problems (DRPs) associated …
Nearly half of hospitalized kidney patients faced drug problems linked to stomach acid reducers. Other medicines and dialysis types also rai…
Narrative review discusses renal risks in inflammatory bowel disease patients
Kidney risks for people with inflammatory bowel disease remain unclear and need more study
This narrative review examines renal complications in individuals with inflammatory bowel disease.
People with inflammatory bowel disease face kidney risks, but current evidence relies on animal studies and lacks human proof.