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Renal impairment

Part of Kidney Diseases

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Renal impairment

37 trials tracked for Renal impairment: 1 in phase 3 or 4.

37Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 1 Phase 2 5 Phase 1 28 Other / NA 3
  1. Phase 4 An Open-label, Non-randomized, Parallel Group Study in Subjects With Mild, Moderate, Severe, or No Renal Impairment Completed
  2. Phase 2 Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim2) Completed
  3. Phase 2 Neuromuscular Blockade in Patients With Severe Renal Impairment Completed
  4. Phase 2 Study of PK/PD, Safety and Tolerability of LIK066 in Patients With Decreased Renal Function. Completed
  5. Phase 2 Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim3) Completed
  6. Phase 2 Effect of Febuxostat on Renal Function in Patients With Gout and Moderate to Severe Renal Impairment Completed
Show 31 more trials
  1. Phase 1 Single-Dose Study to Evaluate the PKs of Pretomanid in Participants With Renal Impairment Compared to Participants With Normal Renal Function Completed
  2. Phase 1 A Study to Evaluate Molnupiravir (MK-4482; MOV) in Participants With Severe Renal Impairment (MK-4482-003) Completed
  3. Phase 1 A Renal Impairment Study for PF-04965842 Completed
  4. Phase 1 Assessment of Renal Function by Multiparametric MRI Completed
  5. Phase 1 A Study of Belzutifan (MK-6482) in Participants With Renal Impairment (MK-6482-021) Completed
  6. Phase 1 The Pharmacokinetics of Grazoprevir (MK-5172) and Elbasvir (MK-8742) in Participants With Renal Insufficiency (MK-5172-050) Completed
  7. Phase 1 STUDY OF PF-06882961 IN PARTICIPANTS WITH TYPE 2 DIABETES MELLITUS WITH VARYING DEGREES OF RENAL IMPAIRMENT AND PARTICIPANTS WITHOUT RENAL IMPAIRMENT Completed
  8. Phase 1 Pharmacokinetics Of CP-690,550 In Patients With Impaired Renal Function Completed
  9. Phase 1 Study to Compare a Dose of Telotristat Etiprate in Subjects With Renal Impairment With Matched Subjects With Normal Renal Function Completed
  10. Phase 1 Renal Impairment Study of PF-06700841 Completed
  11. Phase 1 Study of Pharmacokinetics of a Single IV Dose of CB-238,618 in Subjects With Varying Degrees of Renal Impairment Compared to Healthy Subjects (MK-6183-001) Completed
  12. Phase 1 Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Normal Renal Function or With Severe Renal Impairment Completed
  13. Phase 1 Pharmacokinetics (PK) and Safety of a Single Intravenous (IV) Dose of MK-3866 in Participants With Impaired Renal Function and in Healthy Controls (MK-3866-005) Completed
  14. Phase 1 Phase I Open-label Study to Evaluate Pharmacokinetics of TAK-272 in Participants With Renal or Hepatic Impairment Completed
  15. Phase 1 Renal Impairment Study of PF-07321332 Boosted With Ritonavir in Adult Participants With Renal Impairment and in Healthy Participants With Normal Renal Function. Completed
  16. Phase 1 Pharmacokinetics of Sugammadex (MK-8616) in Participants With Moderate and Severe Renal Insufficiency (MK-8616-105) Completed
  17. Phase 1 A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008) Completed
  18. Phase 1 A Study to Determine the Pharmacokinetics, Pharmacodynamics, and Tolerabiltiy of Betrixaban in Patients With Mild, Moderate, and Severe Renal Impairment Completed
  19. Phase 1 Lorlatinib Renal Impairment Study Completed
  20. Phase 1 Multiple Dose Study to Evaluate the Safety of Multiple Doses of Denosumab 120 mg in Adults With Severe Chronic Kidney Disease (CKD) and CKD on Dialysis Completed
  21. Phase 1 A Study Evaluating the Pharmacokinetics of Doravirine (MK-1439) in Participants With Severe Renal Impairment (MK-1439-051) Completed
  22. Phase 1 Phase 1 Study of PK and Safety of HM15912 (Sonefpeglutide) in Subjects With Normal and Severe Kidney Function Completed
  23. Phase 1 A Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics (PK) of a Single Intravenous (IV) TAK-954 Completed
  24. Phase 1 PK and PD Study of IDN-6556 in Subjects With Severe Renal Impairment and Matched Healthy Volunteers Completed
  25. Phase 1 Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Renal Impairment Completed
  26. Phase 1 Effect of Renal Impairment on the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Ertugliflozin in Participants With Type 2 Diabetes Mellitus (MK-8835-009) Completed
  27. Phase 1 Safety, Pharmacokinetics (PK), And Hematological Activity Of AMD3100 (Plerixafor) In Subjects With Renal Impairment Completed
  28. Phase 1 A Study of Mobocertinib Capsules in People With Severe Kidney Problems and People With Healthy Kidneys Completed
  29. N/A Renal Perfusion, Filtration and Oxygenation During Cardiopulmonary Bypass (CPB) Completed
  30. N/A Incidence of HANA Conditions in HIV-infected Individuals Completed
  31. N/A Observational Study of Methoxy Polyethylene Glycol Epoetin Beta Daily Use in Participants on Peritoneal Dialysis Completed

Showing the 37 most-cited and recently-updated of 37 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

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