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N/A N=41 Randomized Triple-blind Treatment

Study of PEMF (Pulsed Electromagnetic Field) Therapy in the Treatment of Persistent Post-Operative Pain Following Lumbar Surgery

Lumbar Surgery

Enrolled (actual)
41
Serious AEs
0.0%
Results posted
Feb 2017
Primary outcome: Primary: Percent Change From Baseline in Pain Scores — -25.6; -40.2; -18.6 Percent Difference

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Provant (Device)
Age
Adult, Older Adult · 22+ yrs
Sex
All
Sponsor
Regenesis Biomedical, Inc.
Primary completion
Aug 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Percent Change From Baseline in Pain Scores
-25.6; -40.2; -18.6

Summary

To demonstrate the analgesic effectiveness of 2 modalities of PEMF treatment compared to sham treatment in patients with persistent pain following lumbar surgery when treatment is administered twice daily over a 60 day period.

Eligibility Criteria

Inclusion Criteria

  • Subject age is greater than or equal to 22 years.
  • Subject has undergone one or two anatomically successful lumbar back surgeries for the treatment of low back pain.
  • Subject has persistent pain in the low back and/or radiating pain to leg(s) for > 3 months and 30 days prior to the Screening Visit.
  • Average Pain Intensity (calculated as the mean of the daily Average Pain Intensity scores for either back and/or leg) is ≥ 3 and 100 mg oral Morphine Sulfate equivalents per day during the 10 day run-in period.
  • Standard deviation around the mean of the average pain intensity scores during the 10 day run-in period is > 2.0.
  • Subject has a Body Mass Index (BMI) > 38 kg/m2.
  • Subject is currently pregnant or planning on becoming pregnant prior to Day 75.
  • Subject has been previously treated with the PROVANT Therapy System.
  • Subject is in current litigation regarding back pain or is receiving Worker's Compensation.
  • Subject is unwilling or unable to follow study instructions, comply with the treatment regimen, study visits, and ePRO assessments.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02416973). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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