N/A N=92 Epidural Neuroplasty for the Treatment of Herniated Lumbar Disk
Herniated Lumbar Disc
Primary: Pain Assessed by Visual Analogue Scale — 5.63; 5.92 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=40 Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy
Radiculopathy · Herniated Disk
Primary: VAS for Lumbar Pain in 3 Months — 2.63; 4.53 units on a scale — p=0.05
N/A N=100 Sagittal Plane Shear Index for Planning Lumbar Stenosis Surgery
Lumbar Spinal Stenosis · Spondylolisthesis
Primary: Proportion of Surgical Plans Recorded Prior to the SPSI Report That Are Altered After Integration of SPSI Into the Surgical Planning — 47; 22; 6 Surgical plans
N/A N=10 Postoperative Telehealth Mindfulness Intervention After Spine Surgery
Chronic Low-back Pain · Postsurgical Pain · Opioid Use
Primary: Feasibility - Study Retention — 3 Participants
N/A N=158 Central Nervous System Amplification in Lumbar Failed Back Surgery Syndrome
Chronic Pain
Primary: Clinical Pain Severity - 50% Reduction Responders vs Nonresponders — -83; 0 percentage of change
N/A N=120 Effectiveness of Percutaneous Lumbar Epidural Adhesiolysis and Neurolysis on Low Back Pain
Low Back Pain
Primary: Numeric Pain Rating Score — 7.9; 8.1; 4.9; 3.4 units on a scale — p=<0.001
Phase 4 N=83 Lumbar Plexus Block for Postoperative Pain Control After Hip Arthroscopy. A Randomized Controlled Trial
Postoperative Pain
Primary: Numeric Rating Scale (NRS) Pain at Rest (0-10) on Day of Surgery Prior to Discharge — 3.3; 4.2 units on a scale
Phase 4 N=146 Herniectomy Versus Herniectomy With a Spinal Stabilization System for the Treatment of Complex Disc Disease
Sciatica · Back Pain
Primary: To Demonstrate a Statistically Significant Difference in the Relief of Back Pain Between Both Treatment Groups. The Endpoint Will be the Difference Between Baseline and…
N/A N=259 Study Comparing 3 Different Treatments for Arthritis of the Lower Back (Lumbar Spinal Stenosis)
Lumbar Spinal Stenosis
Primary: Swiss Spinal Stenosis (SSS) Questionnaire Score — -2.0; -1.7; -4.1 units on a scale — p=0.73
N/A N=100 Safety and Efficacy of DepoDur in Lumbar Spine Surgery Patients
Lumbar Spine Surgery
Primary: Number of Patients Enrolled and Recieving Injection — 98 participants
N/A N=196 Efficacy of Acupuncture for Lumbar Spinal Stenosis
Lumbar Spinal Stenosis · Intermittent Claudication
Primary: The Change in Modified Roland-Morris Disability Questionnaire (RMDQ) Score From Baseline — -4.3; -3.0 score on a scale
Phase 4 N=6 Lofexidine for Adults Undergoing Lumbar Spine Surgery
Opioid Withdrawal
Primary: Opioid Tapering — 5 Participants
N/A N=72 Minimal Access Surgical Technique (MAST) in Obese Patients in Degenerative Lumbar Disease
Degenerative Lumbar Disease
Primary: Postoperative Complications in the BMI Groups During Post Operative Hospitalization. — 8; 9; 20 Events during hospitalization
Phase 3 N=401 Corticosteroid Lumbar Epidural Analgesia for Radiculopathy
Lumbosacral Radicular Pain
Primary: Mean Change From Baseline (Day 1) to Week 4 in the Mean Numeric Pain Rating Scale (NPRS) Average Pain Score in the Affected Leg — -2.34; -1.16 Change in score on a scale…
N/A N=41 Study of PEMF (Pulsed Electromagnetic Field) Therapy in the Treatment of Persistent Post-Operative Pain Following Lumbar Surgery
Lumbar Surgery
Primary: Percent Change From Baseline in Pain Scores — -25.6; -40.2; -18.6 Percent Difference
Phase 4 N=400 Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial)
Spinal Stenosis · Low Back Pain
Primary: Roland Morris — 11.8; 12.5 units on a scale
N/A N=53 Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages
Lumbar Degenerative Disc Disease · Lumbar Spinal Stenosis · Lumbar Spondylolisthesis
Primary: Interbody Radiographic Fusion Rate — 27; 10; 6; 24 Cages/Spinal Levels
N/A N=10 The Vertos MILD™ Preliminary Patient Evaluation Study
Lumbar Spinal Stenosis
Primary: Changes in Back Pain as Measured by a 10-point Visual Analog Scale (VAS). — 3.3 units on a scale
N/A N=337 5-Year Global Study on MAST™ Minimally Invasive Fusion Procedures to Treat Degenerative Lumbar Spine (MASTERS-D2)
Intervertebral Disc Degeneration
Primary: Change (Preop-postop) of Disability, Oswestry Disability Index (ODI) at 3 Months as Compared to Baseline in DDD Patients With Spondylolisthesis — 23.19; 26.08 change of…
N/A N=56 Enhanced Recovery After Spine Surgery
Enhanced Recovery After Surgery · Spine Surgery
Primary: Patient Score on QoR40 Inventory. — 179.4; 170.3 scores on a scale
N/A N=239 Clinical Trial Comparing Decompression With and Without Coflex™ Interlaminar Technology Treating Lumbar Spinal Stenosis
Spinal Stenosis
Primary: Change in ODI From Baseline to 24 Months — -19.0; -22.5 percentage points
N/A N=178 Lumbar Degenerative Disc Disease Treated With Anterior Tension Band System (ATB) With ALIF/FRA Spacer
Lumbar Degenerative Disc Disease
Primary: Number of Subjects With Successful Radiographic Fusion — 90 Participants
N/A N=15 Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® Disc Augmentation System: A Pilot Study
Low Back Pain
Primary: Numbers and Types of Adverse Events (Only Number of Events is Reported in This Section - See Adverse Events Section for Further Detail) — 17 Events
N/A N=46 Vertos Mild - Post Market Patient Outcomes
Lumbar Spinal Stenosis
Primary: Pain as Measured by Visual Analog Scale (VAS). — 2.17 units on a scale — p=<0.0001
Phase 3 N=991 A Study of SI-6603 in Patients With Lumbar Disc Herniation
Intervertebral Disc Disease · Lumbar Disc Disease
Primary: Number of Participants With Treatment-Emergent Adverse Events (TEAE) — 615 Participants
N/A N=120 Study of Opioid Use After Lumbar and Cervical Spine Surgery
Low Back Pain · Opiate Addiction · Neck Pain
Primary: Number of Opioid Medication Prescriptions — 5.0; 5.1 prescriptions count
N/A N=64 Evaluation of 3D Machine-vision Image Guided Surgery Spine Navigation
Spinal Stenosis, Lumbar Region · Spondylolisthesis
Primary: Mean Total Length of Operative Time — 218; 218.5 minutes
N/A N=252 A Prospective, Multicenter Observational Study on MAST™ (Minimal Access Spinal Technologies) Fusion Procedures for the Treatment of the Degenerative Lumbar Spine
Degenerative Lumbar Spine Causing Back and/or Leg Pain · Lumbar Spine Degeneration
Primary: Time From Surgery to First Ambulation. — 1.3 Days from surgery to first ambulation
N/A N=299 Evaluation of Spine Surgery Analgesic Pathway
Posterior Spine Surgery
Primary: Quality of Recovery — 109; 109 units on a scale — p=0.92
N/A N=248 Postoperative Management for Degenerative Spinal Conditions
Spinal Degenerative Disorder
Primary: Oswestry Disability Index (ODI) — 43.6; 45.46; 31.31; 31.19 units on a scale