Phase 4 Completed N=99 Randomized Quadruple-blind Supportive Care

A Randomized Controlled Trial of Oral Acetaminophen for Analgesic Control After Transvaginal Oocyte Retrieval

Postoperative Pain

Source: ClinicalTrials.gov NCT02418182 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Feb 2020

Primary outcomePrimary: Median of Cumulative Pain Scores Up to 60 Minutes Post Procedure — 2; 2 score on a scale

◆ Published Evidence

No publication linked

No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.

Summary

Current standard of care is no pretreatment medications before the egg retrieval, and the investigators would like to evaluate if preoperative Tylenol improves procedure and post procedure pain control over the current practice (no pre-treatment). Specifically, this study will compare Tylenol with a placebo when given before retrieval procedures. The investigators believe that if Tylenol can offer better analgesic relief than no pretreatment medications, then it may reduce the amount of narcotics needed by patients during and after the procedure and contribute to better patient satisfaction. . This study will enroll 100 participants all from University of Alabama at Birmingham (UAB).

Outcome Measures

Outcome	Result	p-value
PRIMARY Median of Cumulative Pain Scores Up to 60 Minutes Post Procedure	2; 2	—
PRIMARY Median of Cumulative Pain Scores Up to 24 Hours Post Procedure	1; 2	—
SECONDARY Number of Participants With Use of Analgesics up to 60 Minutes Post Procedure	11; 18	—
SECONDARY Number of Participants With Use of Analgesics in the First 24 Hours After Discharge	25; 27	—

Eligibility Criteria

Inclusion Criteria

English Speaking
Undergoing Transvaginal Oocyte Retrieval Procedure

Exclusion Criteria

Acetaminophen allergy
Opioid dependency

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02418182). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.