Phase 4
Completed N=34
Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia
Schizophrenia · Cigarette Smoking
Source: ClinicalTrials.gov NCT02420015 ↗
Enrolled (actual)
34
Serious AEs
14.7%
Results posted
Jul 2019
Primary outcomePrimary: Number of Participants Who Self-report Prolonged Abstinence — 6; 3 Participants
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
This study is designed to evaluate if a treatment the investigators call iCOMMIT is effective at helping smokers with schizophrenia stop smoking. iCOMMIT is a smoking cessation treatment that combines mobile technology with behavioral strategies, counseling, and medications.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants Who Self-report Prolonged Abstinence |
6; 3 | — |
| PRIMARY Number of Participants Whose Prolonged Abstinence is Bio-verified |
3; 2 | — |
| SECONDARY Number of Participants Who Report 7 Day Point Prevalence Abstinence |
4; 2 | — |
| SECONDARY Number of Participants Who Report 30 Day Point Prevalence Abstinence |
1; 2 | — |
| SECONDARY Number of Participants Who Report 7 Day Point Prevalence Abstinence |
4; 2 | — |
| SECONDARY Number of Participants Who Report 30 Day Point Prevalence Abstinence |
1; 2 | — |
Eligibility Criteria
Inclusion Criteria
- Currently smoke at least ten cigarettes a day
- Have been smoking for at least one year
- Meet criteria for schizophrenia, schizoaffective disorder, or another psychotic disorder based on structured clinical interview
- Can speak and write fluent conversational English
- Are between 18 and 70 years of age
- Are willing to make a smoking cessation attempt
- Score 26 or higher on the Montreal Cognitive Assessment
Exclusion Criteria
- Have a history of myocardial infarction in the past 6 months
- Have a contraindication to NRT with no medical clearance from the primary care provider or study physician
- Use and unwillingness to stop use of other forms of nicotine such as cigars, pipes, or chewing tobacco
- Are pregnant
- Meet criteria for a current manic episode based on structured clinical interview
- Are currently enrolled in another smoking cessation trial
- Are currently imprisoned or in psychiatric hospitalization
Data sourced from ClinicalTrials.gov (NCT02420015). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.