Mode
Home
Research
Clinical Trials Drug Pipeline Weekly Digests
Reference
Conditions Medications
Community
Questions
Text Size
Log in / Sign up
N/A N=35 Randomized Double-blind Treatment

Pilot Study of Combined Treatment for Veterans With Chronic Pain & Opiate Misuse

Chronic Pain · Problematic Opioid Use

Bottom Line

View on ClinicalTrials.gov: NCT02423772 ↗
Enrolled (actual)
35
Serious AEs
0.0%
Results posted
Nov 2024
Primary outcome: Primary: Patient Reported Outcomes Measurement Information System (PROMIS) - Pain Behavior — 66.7; 66.0; 64.3; 66.8 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Acceptance and Commitment Therapy + Mindfulness-Based Relapse Prevention + Treatment as Usual (TAU) (Behavioral)
Age
Adult, Older Adult · 21+ yrs
Sex
All
Sponsor
University of New Mexico
Primary completion
Jul 2018

Outcome Measures

OutcomeResultp-value
PRIMARY
Patient Reported Outcomes Measurement Information System (PROMIS) - Pain Behavior		 66.7; 66.0; 64.3; 66.8 —
PRIMARY
Patient Reported Outcomes Measurement Information System (PROMIS) - Pain Interference		 66.7; 65.2; 64.3; 70.1 —
PRIMARY
Current Opioid Misuse Measure (COMM)		 16.2; 17.4; 10.6; 16.1 —

Summary

Chronic pain and misuse of opioids is a major public health problem, particularly in military veterans. The major goal of this project is to test the efficacy of an innovative behavioral treatment for chronic pain patients who are misusing prescription opiates. This project supports the strategic goals of National Center for Complementary and Integrative Health (NCCIH) and National Institute on Drug Abuse by examining a difficult and understudied problem with the ultimate goal of impacting scientific knowledge and human health.

Eligibility Criteria

Inclusion Criteria

  • Aged 21-65 years old
  • Diagnosis of chronic pain condition
  • Pain severity over the past seven days of four or greater on a 0-10 scale
  • Prescribed opioids for the treatment of chronic pain for the past 90 days or longer
  • Ability to read written English

Exclusion Criteria

  • Meet diagnostic criteria for current substance abuse/dependence on a drug other than opioids
  • Meet diagnostic criteria for a current or past DSM diagnosis of schizophrenia, delusional disorder, psychotic or dissociative disorders,
  • Currently prescribed medications for opioid addiction (e.g., Buprenorphine/Naloxone/Suboxone).
  • History of suicide attempts or inpatient hospitalization for risk of suicide in the past six month. In addition, we will screen for significant suicidal
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02423772). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

Back to search