N/A
Completed N=35
Pilot Study of Combined Treatment for Veterans With Chronic Pain & Opiate Misuse
Postoperative Pain · Problematic Opioid Use
Source: ClinicalTrials.gov NCT02423772 ↗
Enrolled (actual)
35
Serious AEs
0.0%
Results posted
Nov 2024
Primary outcomePrimary: Patient Reported Outcomes Measurement Information System (PROMIS) - Pain Behavior — 66.7; 66.0; 64.3; 66.8 units on a scale
Summary
Chronic pain and misuse of opioids is a major public health problem, particularly in military veterans. The major goal of this project is to test the efficacy of an innovative behavioral treatment for chronic pain patients who are misusing prescription opiates. This project supports the strategic goals of National Center for Complementary and Integrative Health (NCCIH) and National Institute on Drug Abuse by examining a difficult and understudied problem with the ultimate goal of impacting scientific knowledge and human health.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Patient Reported Outcomes Measurement Information System (PROMIS) - Pain Behavior |
66.7; 66.0; 64.3; 66.8 | — |
| PRIMARY Patient Reported Outcomes Measurement Information System (PROMIS) - Pain Interference |
66.7; 65.2; 64.3; 70.1 | — |
| PRIMARY Current Opioid Misuse Measure (COMM) |
16.2; 17.4; 10.6; 16.1 | — |
Eligibility Criteria
Inclusion Criteria
- Aged 21-65 years old
- Diagnosis of chronic pain condition
- Pain severity over the past seven days of four or greater on a 0-10 scale
- Prescribed opioids for the treatment of chronic pain for the past 90 days or longer
- Ability to read written English
Exclusion Criteria
- Meet diagnostic criteria for current substance abuse/dependence on a drug other than opioids
- Meet diagnostic criteria for a current or past DSM diagnosis of schizophrenia, delusional disorder, psychotic or dissociative disorders,
- Currently prescribed medications for opioid addiction (e.g., Buprenorphine/Naloxone/Suboxone).
- History of suicide attempts or inpatient hospitalization for risk of suicide in the past six month. In addition, we will screen for significant suicidal
Data sourced from ClinicalTrials.gov (NCT02423772). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.