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N/A Completed N=84 Randomized Double-blind Basic Science

The Effect of Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

Antisocial Behavior · Aggression
Source: ClinicalTrials.gov NCT02427672 ↗
Enrolled (actual)
84
Serious AEs
0.0%
Results posted
Aug 2019
Primary outcomePrimary: Change in Antisocial Behavior Inclinations at 24 Hours — 1.41; 3.05 score on a scale

Summary

This study investigates the effect of upregulating prefrontal cortex activity on antisocial and aggressive behavior and risk factors for such behavior. In the double-blind, randomized controlled trial, participants will undergo anodal transcranial direct current stimulation bilaterally to the dorsolateral prefrontal cortex or a sham stimulation. During and after stimulation, they will complete survey and laboratory measures assessing antisocial and aggressive behavior and risk factors for antisocial and aggressive behavior. Heart rate and skin conductance will also be measured.

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Antisocial Behavior Inclinations at 24 Hours
1.41; 3.05
PRIMARY
Number of Pins Inserted Into a Virtual Voodoo Doll at 24 Hours
5.31; 2.62

Eligibility Criteria

Inclusion Criteria

  • Above 18 years of age
  • Able to understand the nature of the study and give informed consent

Exclusion Criteria

  • History of or active neurologic, cardiovascular, or psychiatric disease
  • Currently consuming anti-convulsant, anti-psychotic, or sedative/hypnotic medications
  • Currently consuming anti-depressants
  • History of seizures
  • Metallic implants on the scalp
  • Participation in other transcranial magnetic stimulation (TMS) or tDCS experiments on the same day
  • History of adverse reactions to tDCS
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02427672). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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