N/A N=32 The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior
Antisocial Behavior · Aggression
Primary: Number of Pins Inserted Into a Virtual Voodoo Doll After 48 Hours — 3.77; .64 pins
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=84 The Effect of Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior
Antisocial Behavior · Aggression
Primary: Change in Antisocial Behavior Inclinations at 24 Hours — 1.41; 3.05 score on a scale
N/A N=11 Conduct Disorder in Prison: Search for Prospective and Retrospective Recurring and Contextual Elements
Mental Disorders
Primary: The Number of Individuals Diagnosed With Antisocial Personality Disorder in Rochefort Prison With Aberrant Driving Behaviors. — 9 participants
N/A N=13 Tx for Child Sexual Behavior Problems
Sexual Behavior
Primary: Child Sexual Behavior on the Child Sexual Behavior Inventory (CSBI) — 28.8; 18.1 Scores on a scale
N/A N=48 Behavioral Treatment for Children With Conduct Problems and Callous-Unemotional Traits
Conduct Disorder · Oppositional Defiant Disorder
Primary: Conduct Problems — 0.76; 1.08; 0.41; 0.92 Number of conduct problems per day
Phase 4 N=104 Body and Social Behavior
Psychology, Social · Inflammation · Defeat, Social
Primary: IL-6 Levels 24 Hours After Vaccine — 0.40; 0.23 log pg/mL — p=<0.001
N/A N=30 Identifying Precursors to Severe Problem Behavior
Problem Behavior · Aggression
Primary: Severe Problem Behavior (SPB)
Phase 2 N=54 Effect of Oxytocin Nasal Sprays on Social Behavior in Social Anxiety Disorder
Social Anxiety Disorder
Primary: Social Cooperation — 4.42; 4.69 Ball tosses
N/A N=17 Pediatric Aggression and Violence
Pediatric Aggression and Violence
Primary: Salivary Hormone Correlation With Brief Rating of Aggression by Children and Adolescent (BRACHA) Score — 0.8; 0.4; 0.3; 0.4 ul/dL
Early Phase 1 N=80 Alcohol, Behavior, and Brain Imaging
Alcohol Drinking · Binge Drinking · Drinking Behavior
Primary: Stop Signal Task (SST) — 255; 215 milliseconds
N/A N=16 Behavioral Activation (BA) for Medication-responsive Chronically Depressed Patients With Impaired Social Functioning
Persistent Depressive Disorder
Primary: Paid Work Hours at Week 12 — 30.3 hours — p=0.005
N/A N=54 Computer-based Social Skills Training for Autism Spectrum Disorder
Autism Spectrum Disorder
Primary: Ekman-60 Faces Test — 38.56; 32.03 score on a scale
Phase 3 N=141 Treating Violence-Prone Substance Use Disorder Patients
Substance-related Disorders · Violence
Primary: Addiction Severity Index Legal Composite — .038; .012 units on a scale
N/A N=13 Efficacy of Aripiprazole Versus Placebo in the Reduction of Aggressive and Aberrant Behavior in Autistic Children
Autism
Primary: Clinical Global Impression Improvement (CGI-AD) — 3.83; 4.25; 2.67; 4.25 score on a scale
Phase 1 N=8 Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With Autism
Autism Spectrum Disorder · Aggression · Irritability
Primary: Change From Baseline in Aberrant Behavior Checklist Irritability Subscale (ABC-I) — -12; -7 units on a scale — p=.44
N/A N=9 Behavioral Economics and Communication
Problem Behavior
Primary: Averge of Aappropriate Communication Responses — 3.33 direct observation of 5-min sessions
N/A N=106 Assessment and Treatment of Social Skills Deficits in Individuals With Social Phobia
Social Phobia
Primary: Social Phobia Remission
Phase 2 N=105 The Impact of Psychopathic Traits on the Efficacy of a Substance Use Intervention
Substance Use · Psychopathy
Primary: Percent Days Abstinent Per Month From Drug Use — 46.92; 55.16 percentage of days abstinent — p=.02
N/A N=565 Single-Session Intervention Targeting Self-Injurious Behavior in Adolescents
Nonsuicidal Self Injury · Self Hatred · Suicidal Thoughts
Primary: Nonsuicidal Self-injury Frequency in the Past 3 Months — 15.81; 13.93; 22.72; 23.85 Nonsui behaviors (i.e., number of times)
N/A N=38 Attachment and Biobehavioral Catch-up and Depression Treatment
Maternal Depression · Child Behavior Problem
Primary: Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Depression Score — 6.70; 6.98 units on a scale — p=.85
Phase 4 N=40 Neural and Behavioral Effects of Oxytocin in Autism Spectrum Disorders
Autism Spectrum Disorders
Primary: Change From Baseline in Brain Activity During Task (Task-based fMRI) After a Single Dose of Nasal Spray — 0.11; -0.26; -0.15; -0.16 Change-from-baseline (BOLD response)
N/A N=24 Wiring Adolescents With Social Anxiety Via Behavioral Interventions
Social Anxiety
Primary: Ecological Momentary Assessment (EMA) Adherence — 53 percentage of participants
Phase 2 N=6 Propranolol for Challenging Behaviors in Autism
Autism Spectrum Disorder · Developmental Disability · Aggression
Primary: Aberrant Behavior Checklist--Community (ABC-C) Irritability Subscale Scores — 14.0; 18.50 score on a scale — p=0.12
N/A N=22 Treatment of Aggression, Anger and Emotional Dysregulation in Borderline Personality Disorder
Borderline Personality Disorder
Primary: Self-Report of Difficulties in Emotion Regulation (DERS) — 101.5; 54.8; 120.5; 56.6 units on a scale — p=<0.004
N/A N=40 Stimulating the Social Brain
Healthy Adults
Primary: Change in General Paranoid Ideation for Active vs. Sham Simulation — 1.60; .73 score on a scale