N/A N=11 Randomized Single-blind Treatment

Capsaicin 8% Patch for Spinal Cord Injury Neuropathic Pain

Spinal Cord Injuries · Neuropathic Pain

Bottom Line

View on ClinicalTrials.gov: NCT02441660 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Oct 2022

Primary outcome: Primary: Change in Pain Relief With Visual Analog (VAS) Pain Scale — 3.586; 5.494; 4.041; 5.677 score on a scale

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Capsaicin 8% Patch (Drug); Low Dose Capsaicin 0.025% Well Patch (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: The University of Texas Health Science Center at San Antonio
Primary completion: Jul 2021

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Pain Relief With Visual Analog (VAS) Pain Scale	3.586; 5.494; 4.041; 5.677; 4.984; 5.768	—
PRIMARY Change in Quality of Life as Measured by the World Health Organization Quality of Life (WHOQOL-BREF)	79.26; 80.91; 80.91; 85.42; 74.90; 87.42	—
PRIMARY Change in Spinal Cord Independence Measure (SCIM)	20.32; 18.86; 20.70; 18.66; 19.23; 18.86	—

Summary

A prospective case control study to determine the effectiveness and longevity of 8% capsaicin patch(es) in treating neuropathic pain in persons with spinal cord injury. The investigators will study spinal cord injury patients at South Texas Veterans Health Care Systems Spinal Cord Injury inpatient unit and outpatient clinics.

Eligibility Criteria

Inclusion Criteria

Diagnosis of SCI
Neuropathic pain below level of injury
Surface area of pain no larger than 2 patches
Failed or did not tolerate gabapentin 3600mg/day, pregabalin 600mg/day, capsaicin cream and/or lidocaine cream
Skin over painful area intact

Exclusion Criteria

Pain over open wound
Previously documented allergy to capsaicin
Superficial burn over area of pain
Premorbid (before SCI) neuropathic pain
HIV/AIDS neuropathy

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02441660). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.