N/A
Completed N=122
An Investigation Into the Effects of a Wild Blueberry Powder and a Wild Blueberry Extract on Cognition in Older Adults
Source: ClinicalTrials.gov NCT02446314 ↗Enrolled (actual)
122
Serious AEs
0.0%
Results posted
Aug 2019
Primary outcomePrimary: Proportion of Words Correctly Recognised. — 0.86; 0.85; 0.79; 0.90 proportion of words correctly recognised
Summary
The purpose of this study is to determine whether a 6 month dietary intervention with wild blueberry powder and extract stabilised with L-cysteine and L-glutathione have an effect on cognitive performance in participants aged between 65 - 80.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Proportion of Words Correctly Recognised. |
0.86; 0.85; 0.79; 0.90; 0.90; 0.88 | — |
| PRIMARY Total Number of Correct Sequences Recalled |
15.15; 14.27; 15.42; 16.19; 15.56; 16.348 | — |
| PRIMARY Combined Z Score of Delayed Words Recalled, Words Recognised, and Pictures Recognised. |
0.19; 0.08; 0.02; 0.28; 0.31; 0.13 | — |
| SECONDARY Combined Z Score of Mean Reaction Time Scores for Incongruent Attention Network and Stroop Task Trials. |
0.003; 0.009; -0.137; -0.037; -0.101; -0.176 | — |
| SECONDARY Combined Z Score of Proportion of Immediate Words Recalled, Number of Correct Serial 3 and Serial 7 Subtractions, Sternberg Task Coefficent of the Line |
0.12; -0.03; -0.13; 0.03; 0.1; -0.01 | — |
| SECONDARY Systolic Blood Pressure |
124.11; 124.51; 125.16; 118.62; 119.63; 122.39 | = .04 sig |
| SECONDARY Diastolic Blood Pressure |
72.70; 74.85; 72.30; 72.30; 71.71; 73.54 | > .05 |
| SECONDARY Heart Rate |
68.33; 69.16; 66.07; 67.56; 68.62; 67.47 | > .05 |
| SECONDARY Positive Affect Score |
31.29; 31.18; 32.10; 31.30; 31.06; 31.07 | > .05 |
| SECONDARY Negative Affect Score |
12.04; 13.14; 11.72; 11.53; 12.17; 12.18 | > .05 |
Eligibility Criteria
Inclusion Criteria
- Overall healthy volunteers as proven by medical history and/or physical examination and of all ethnicity and socioeconomic status
- Free-living
- Subjects with subjective memory complaints
- MMSE: 24-30
- Subjects are willing to maintain their normal eating habits and exercise habits to avoid changes in body weight over the duration of the study
- Being willing to complete the food diaries and questionnaires
- Able to give signed written informed consent
- Signed informed consent form
Exclusion Criteria
- Use of complementary and alternative medicine
- History of metabolic disorder, diabetes, substance abuse
- Subjects diagnosed with psychiatric or neurological conditions
- Subjects using medications that might affect the outcome measures (such as antidepressant and sleeping medication), or planned changes
Data sourced from ClinicalTrials.gov (NCT02446314). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.