Food insecurity linked to poorer diet and higher obesity risk in older adults
Food Insecurity Linked to Poorer Diet and Obesity in Older Adults
This narrative review synthesizes evidence linking food insecurity and financial hardship to poorer diet quality and higher odds of overweig…
Older adults facing food insecurity eat worse and are more likely to be obese, a review finds.
Younger US men show sharp loneliness increase, older men stable, systematic review finds
Loneliness Linked To Health Risks In Men Across The United States
This systematic review of 30 core studies on US men found no widespread epidemic of loneliness, but younger men (ages 18–29) show a sharp in…
A review of 30 studies finds loneliness in men is linked to depression, heart disease, and higher mortality, with younger men facing a sharp…
Framingham cohort links longitudinal brain atrophy patterns to cognitive decline and AD biomarkers in community-based participants
Brain shrinkage patterns predict Alzheimer's risk in older adults
This community-based cohort study of 300 participants from the Framingham Heart Study analyzed longitudinal brain atrophy patterns using MRI…
A study of 300 older adults found specific brain shrinkage patterns that strongly predict Alzheimer's disease and worse thinking skills.
Living alone not linked to incident dementia but associated with higher institutionalization risk in a cohort of 2,269 individuals
Living Alone Does Not Raise Dementia Risk But Increases Care Needs
This French clinic-based cohort study followed 2,269 individuals with cognitive complaints or mild cognitive impairment for a median of 5 ye…
Living alone does not increase dementia risk, but it does raise the chance of needing nursing home care later.
Menopausal hormone therapy initiation around menopause linked to increased Alzheimer's risk
Hormone Therapy and Dementia: The Truth About Timing
This systematic review and meta-analysis of 213,678 menopausal women found that initiating systemic menopausal hormone therapy (MHT) around …
Many women look to hormone therapy to ease the hot flashes and mood swings of menopause.
Narrative review covers cardiovascular conditions and cognitive decline without reported trial data
Your Heart and Brain Are Talking to Each Other
This narrative review addresses a broad scope of cardiovascular conditions, including stroke, heart failure, atrial fibrillation, and ischem…
Imagine your heart and brain as two best friends who never stop texting each other.
PDE5 inhibitors increased cerebral blood flow in white matter hyperintensity regions in adults with cerebral small vessel disease
An Old Drug Class May Protect the Brain From Silent Damage
This systematic review and meta-analysis evaluated phosphodiesterase-5 inhibitors (sildenafil or tadalafil) versus placebo in 236 adults wit…
Drugs already approved for other conditions may help restore blood flow in a part of the brain that quietly fuels strokes and dementia.
Dementia prevention class shows no effect on dementia onset or insurance certification in observational study
Dementia prevention classes improved function but did not stop disease onset in this study
A retrospective observational study of 578 individuals with mild cognitive decline in three municipalities found no significant association …
Dementia prevention classes improved daily skills and function but did not stop disease onset or reduce long-term care needs in this study.
Occupational noise exposure linked to cognitive decline in cross-sectional study of 170 workers
Loud Job Sites May Be Costing Workers More Than Hearing
A cross-sectional study of 170 noise-exposed workers found hearing loss was significantly associated with cognitive decline.
Hearing protection on a noisy worksite may shield not only your ears but also how sharply your brain works in the years ahead.
BP variability and pulse pressure associated with cognitive decline in type 2 diabetes patients
Blood pressure swings linked to thinking problems in people with type 2 diabetes
A secondary analysis of 9,586 patients with type 2 diabetes from the ADVANCE trial found that higher blood pressure variability and baseline…
For people with type 2 diabetes, big swings in blood pressure are linked to a higher risk of memory and thinking problems down the road.
Social isolation linked to health risks in empty-nest older adults, integrative review finds
How does social isolation affect older adults whose children have moved out?
An integrative review of 14 studies found social isolation among empty-nest older adults over 60 is associated with elevated physical health…
For older adults whose children have moved out, feeling socially isolated is linked to higher risks of death, depression, loneliness, and a …
Research across Cognitive Dysfunction
Related studies from across the Cognitive Dysfunction family.
Combined exercise and diet modestly improves cognition in mild cognitive impairment
Combined exercise and diet plans may help slow thinking problems in older adults with mild memory issues
This systematic review and meta-analysis of 4013 healthy older adults or those with mild cognitive impairment found that combined exercise a…
A large review of over 4,000 people found that mixing exercise with healthy eating might improve overall brain function. However, specific s…
Acupuncture Boosts Cognition in Alzheimer's and Mild Cognitive Impairment
Meta-analysis shows acupuncture improves cognitive function in Alzheimer's and mild cognitive impairment
A meta-analysis of 3362 patients finds acupuncture, alone or with Western medicine, significantly improves cognitive function in Alzheimer's…
A large analysis of 3,362 patients suggests acupuncture may improve cognitive function in Alzheimer's disease and mild cognitive impairment,…
VR and music therapy alleviate anxiety, chronic pain, and cognitive impairment in diverse patients
Virtual reality and music therapy ease anxiety, pain, and brain fog
A scoping review of 34 articles found that integrating Virtual Reality and Music Therapy significantly alleviates symptoms of anxiety, chron…
A review of 34 studies finds VR combined with music therapy significantly reduces anxiety, chronic pain, and cognitive impairment.
SLE linked to 53% higher odds of cognitive impairment in meta-analysis of 7 million
Lupus linked to higher risk of cognitive decline
This meta-analysis of 7 observational studies involving over 7 million participants found that systemic lupus erythematosus (SLE) is signifi…
People with lupus may face 53% higher odds of cognitive impairment, a large analysis finds.
Hypertension history associates with 2.22-fold higher cognitive impairment risk in AF patients
High blood pressure history doubles dementia risk in atrial fibrillation patients
This systematic review and meta-analysis of observational studies found that a history of hypertension is associated with an increased risk …
A history of high blood pressure is linked to a much higher risk of cognitive impairment in people with atrial fibrillation, according to a …
Atractylenolide III shows neuroprotective effects in preclinical CNS disorder models
Atractylenolide III shows promise for brain and nerve injuries in lab models
This narrative review summarizes preclinical evidence that Atractylenolide III exerts neuroprotective effects in models of cognitive impairm…
Atractylenolide III looks like a helpful option for brain and nerve damage in early lab tests, though human trials are needed.
Narrative review suggests music therapy may improve cognition and neuropsychiatric symptoms in cognitive impairment
Music therapy may help minds affected by Alzheimer's and other cognitive conditions
This narrative review examines the role of music therapy for cognitive impairment. The authors suggest that music therapy may improve cognit…
Music therapy might improve thinking and mood for people with Alzheimer's disease, mild cognitive impairment, or Parkinson's-related cogniti…
Systematic review and meta-analysis of retinal biomarkers in frontotemporal dementia and Alzheimer disease
Retinal scans show thinner layers in frontotemporal dementia than Alzheimer disease
This systematic review and meta-analysis synthesized optical coherence tomography data on retinal biomarkers in frontotemporal dementia, Alz…
A new analysis of retinal scans found that people with frontotemporal dementia have thinner eye layers than those with Alzheimer disease or …
Meta-analysis finds higher peripheral Galectin-3 levels in cognitive impairment
People with cognitive impairment had higher blood levels of a protein called Galectin-3 compared to healthy people in this review
This systematic review and meta-analysis compared peripheral Galectin-3 levels between patients with cognitive impairment and healthy contro…
A large review found that people with cognitive impairment have higher levels of a protein called Galectin-3 in their blood. This difference…
Review of ferroptosis role in postoperative cognitive dysfunction in older surgical patients
Aging and surgery may trigger brain cell death in older patients
This narrative review examines the potential role of ferroptosis in postoperative cognitive dysfunction among older surgical patients. The a…
A review suggests aging and surgery might trigger brain cell death in older patients, but scientists are not sure if this process causes the…
tDCS improves global cognition in Alzheimer's and MCI
New meta-analysis finds tDCS improves global cognition in Alzheimer's and mild cognitive impairment
A meta-analysis of 616 patients shows transcranial direct current stimulation significantly improves global cognition in Alzheimer's disease…
A new meta-analysis of 616 patients suggests transcranial direct current stimulation may improve global cognition in Alzheimer's disease and…
Depression linked to higher risk of progression from mild cognitive impairment to Alzheimer's disease and dementia in adults
Depression Linked to Higher Risk of Dementia Progression in Mild Cognitive Impairment
This systematic review and meta-analysis evaluated the association between depression and progression from mild cognitive impairment to Alzh…
A new analysis suggests depression may increase the risk of dementia progression in adults with mild cognitive impairment, though evidence c…
Questions about Cognitive Decline
Do cardiovascular conditions like stroke impact cognitive decline?
Yes, cardiovascular conditions like stroke, heart failure, and atrial fibrillation are linked to increased risk of cognitive decline through shared mechanisms like inflammation and reduced blood flow.
Full answer →Is blood pressure variability a risk for cognitive decline in diabetes?
Yes, blood pressure variability is linked to higher risk of cognitive decline in people with type 2 diabetes, independent of average blood pressure levels.
Full answer →Does social isolation in empty-nest adults increase health risks?
Social isolation in empty-nest adults is linked to higher risks of death, depression, and cognitive decline, though living alone by itself does not necessarily cause dementia.
Full answer →How does occupational noise exposure affect my cognitive decline?
Yes, occupational noise exposure is linked to faster cognitive decline, likely through hearing loss and brain changes, but more research is needed.
Full answer →Does living alone increase my risk of developing dementia?
Research is mixed: some studies link living alone to subjective cognitive decline, but a large French study found no direct link to dementia, though it did increase risk of institutionalization.
Full answer →