N/A N=10,347 Randomized Treatment

Reducing Cardiovascular Risk in Adults With Serious Mental Illness

Chronic Disease · Mental Disorder · Health Behavior · Bipolar Disorder · Schizophrenia

Bottom Line

View on ClinicalTrials.gov: NCT02451670 ↗

Enrolled (actual)

10,347

Serious AEs

16.6%

Results posted

Nov 2019

Primary outcome: Primary: Predicted Annual Rate of Change in 10 Year Risk of Fatal or Nonfatal Heart Attack or Stroke — 14.2; 20.8 percentage of annual rate of change

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Prioritized Clinical Decision Support (Behavioral)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: HealthPartners Institute
Primary completion: Sep 2018

Outcome Measures

Outcome	Result	p-value
PRIMARY Predicted Annual Rate of Change in 10 Year Risk of Fatal or Nonfatal Heart Attack or Stroke	14.2; 20.8	—

Summary

This purpose of this study is to adapt, implement and test the ability of a sophisticated point-of-care electronic health record-based clinical decision support that identifies and prioritizes all available evidence-based treatment options to reduce cardiovascular risk in patients with serious mental illness.

Eligibility Criteria

Inclusion Criteria

Serious Mental Illness diagnosis
Age 18-75
Index visit during the enrollment period
First primary care visit where patient was not at goal for at least one of the six cardiovascular risk factor areas, and patient was not pregnant
One or more post-index visits during the intervention period

Exclusion Criteria

No Serious Mental Illness diagnosis
Under age 18 or over age 75
In hospice or nursing home
At goal for all cardiovascular risk 6 areas
On research exclusion list

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02451670). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.