N/A
N=87
Motor Training in PD
Parkinson Disease
Bottom Line
View on ClinicalTrials.gov: NCT02457832 ↗Enrolled (actual)
87
Serious AEs
0.0%
Results posted
Aug 2024
Primary outcome: Primary: Percent Signal Change — 0; 23; 35 percentage of baseline BOLD signal
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Adapted Tango Dancing (Behavioral); Behavioral Control (BC) Condition (Behavioral)
- Age
- Adult, Older Adult · 40+ yrs
- Sex
- All
- Sponsor
- VA Office of Research and Development
- Primary completion
- Dec 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percent Signal Change |
0; 23; 35 | — |
| PRIMARY Connectivity Strength |
-0.04; -0.03; 0.14 | — |
Summary
The purpose of this research study is to learn more about brain activity when individuals with and without Parkinson disease (PD) move their lower limbs. The investigators also want to see if and how two different types of partnered dance affect brain activity in individuals with and without PD. Testing will take place at the Atlanta VA Medical Center and at Emory University. The investigators expect to enroll about 140 people for this study over a five-year period.
Eligibility Criteria
Inclusion Criteria
- Age 40 - 70 years
- Willingness to spend 1-h in a scanner
- Able to walk with or without an assistive device 10 feet
- Best corrected/aided acuity better than 20/70 in the better eye
- Absence of dementia or vascular cognitive impairment
- Absence of primary memory deficits
Exclusion Criteria
- Deep brain stimulator implants, Metallic implants, fragments, or pacemakers
- Montreal Cognitive Assessment (MocA) score 40 dB
- Peripheral neuropathy
- Untreated Major Depression
- History of stroke, or traumatic brain injury
Data sourced from ClinicalTrials.gov (NCT02457832). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.