N/A
Completed N=14
Diaphragm Ultrasound Vs Transpulmonary Pressure To Set PEEP in ARDS
Source: ClinicalTrials.gov NCT02463773 ↗Enrolled (actual)
14
Serious AEs
0.0%
Results posted
May 2022
Primary outcomePrimary: Feasibility — 14 Participants
Summary
This is a proof of concept study where the investigators aim to study the correlation between the use of a simple bedside ultrasound measurement of diaphragmatic muscle excursion with established (but time consuming) measurements made to optimize an important setting on the mechanical ventilator (positive end expiratory pressure or PEEP) in intubated adults with acute respiratory distress syndrome (ARDS) in the medical ICU.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Feasibility |
14 | — |
Eligibility Criteria
Inclusion Criteria
- Adults older than 18 years old who develop ARDS, as defined by the Berlin criteria, within 72 hours of ICU admission.
Exclusion Criteria
- Any contraindication for nasogastric tube placement including recent injury or pathologic condition of the esophagus.
- Major bronchopleural fistula.
- Solid organ transplant recipient.
- History or current diagnosis of diaphragmatic paralysis.
- Non-conventional mechanical ventilation strategy including high frequency oscillation, airway pressure release ventilation, prone ventilation and extra- corporeal membrane oxygenation.
- Hemodynamic instability defined as MAP<65 with multiple vasopressors.
- Declining to sign consent form.
Data sourced from ClinicalTrials.gov (NCT02463773). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.