Phase 4
Completed N=70
Single-shot TAP Block vs Continuous TAP Block
Source: ClinicalTrials.gov NCT02475031 ↗Enrolled (actual)
70
Serious AEs
—
Results posted
May 2017
Primary outcomePrimary: Total Narcotic Usage at 48 Hours — 2.44; 2.88 mg
◆ Published Evidence
Established
28citations · ~5 / year
Transversus abdominis plane (TAP) block for laparoscopic live donor nephrectomy: Continuous catheter infusion provides no additional analgesic benefit over single-injection ropivacaine.
Summary
The purpose of this study is to determine whether continuous transversus abdominis plane (TAP) block is superior to single shot TAP for postoperative pain after laparoscopic donor nephrectomy
Linked Publications
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Transversus abdominis plane (TAP) block for laparoscopic live donor nephrectomy: Continuous catheter infusion provides no additional analgesic benefit over single-injection ropivacaine.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Total Narcotic Usage at 48 Hours |
2.44; 2.88 | — |
| SECONDARY Secondary Endpoints Measured Will be Total Narcotic Usage at 60 Hours |
14.31; 14.40 | — |
| SECONDARY Average Pain Scores |
5.31; 5.06 | — |
| SECONDARY Nausea Scores at 48 Hours |
0.34; 0.34 | — |
| SECONDARY Sedation Scores at 48 Hours |
0.2; 0.06 | — |
Eligibility Criteria
Inclusion criteria
- Healthy subject undergoing laparoscopic live donor nephrectomy
- (ASA) American Society of Anesthesiologists class 1 or 2
- Age 18 or older, male or female
- Desires TAP block for postoperative pain control
Exclusion criteria
- Any contraindication for TAP block - single or continuous
- History of substance abuse
- Any physical, mental or medical conditions which, in the opinion of the investigators, may confound quantifying postoperative pain resulting from surgery.
- Known allergy or other contraindications to the study medications (Ropivacaine, Normal Saline, Hydromorphone, Oxycodone and Acetaminophen)
Data sourced from ClinicalTrials.gov (NCT02475031) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.