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Phase 4 N=44 Randomized Triple-blind Treatment

Resveratrol for Pain Due to Endometriosis

Endometriosis

Enrolled (actual)
44
Serious AEs
0.0%
Results posted
Aug 2016
Primary outcome: Primary: Pain Scores Measured by VAS (Visual Analog Scale) at Day 42. — 3.2; 3.9 units on a scale — p=0.7

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
Placebo (Drug); Resveratrol (Drug)
Age
Adult · 20+ yrs
Sex
Female
Sponsor
Hospital de Clinicas de Porto Alegre
Primary completion
Nov 2015

Outcome Measures

OutcomeResultp-value
PRIMARY
Pain Scores Measured by VAS (Visual Analog Scale) at Day 42.
3.2; 3.9 0.7
SECONDARY
Serum CA125 Levels at 42 Days
11.7; 13.7 0.1
SECONDARY
Serum Prolactin Levels at 42 Days
12; 11.1 0.8

Summary

This study aims to verify whether the use of 40 mg of resveratrol per day associated with monophasic contraceptive pill (levonorgestrel 0.15mg/ethinyl estradiol 0.03mg) reduces pelvic pain at the end of 2 months of treatment, compared to the use of the pill with placebo.

Eligibility Criteria

Inclusion Criteria

  • Endometriosis diagnosed by laparoscopy

Exclusion Criteria

  • Known allergy to resveratrol
  • Use of gonadotropin or danazol in the last month
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02475564). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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