N/A
N=85
Training Attentional Awareness and Control in ADHD
Attention Deficit Hyperactivity Disorder
Bottom Line
View on ClinicalTrials.gov: NCT02489279 ↗Enrolled (actual)
85
Serious AEs
0.0%
Results posted
Jul 2019
Primary outcome: Primary: Change From Baseline in Conners Continuous Performance Test (CPT) RT Variability Scaled Score — -6.65; 1.84 score on a scale — p=0.026
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Sustained Attention Control (SAC) Method (Behavioral); Scrabble (Behavioral)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- Think Now Incorporated
- Primary completion
- Dec 2016
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change From Baseline in Conners Continuous Performance Test (CPT) RT Variability Scaled Score |
-6.65; 1.84 | 0.026 sig |
| PRIMARY Change From Baseline in Nelson-Denny Reading Test - Comprehension Score |
7.36; 1.04 | 0.014 sig |
| SECONDARY Change From Baseline in Adult Attention-Deficit Hyperactivity Disorder Self-Report Scale (ASRS) - Inattentive Subscale |
-3.29; -4.17 | 0.000001 sig |
| SECONDARY Change From Baseline in Adult Attention-Deficit Hyperactivity Disorder Self-Report Scale (ASRS) - Hyperactive Subscale |
-2.54; -3.13 | 0.00018 sig |
Summary
The purpose of this study is to evaluate the effects of different types of cognitive training on attention in adults with Attention Deficit Hyperactivity Disorder (ADHD) using mobile software on personal mobile devices.
Eligibility Criteria
Inclusion Criteria
- Meet established Diagnostic and Statistical Manual-5 (DSM-5) criteria for ADHD predominately inattentive or combined subtype with clinically significant levels of impairment, diagnosed by structured clinical interview, the Mini International Neuropsychiatric Interview, and corroborating information
- Clinical Global Impression-Severity (CGI-S) score ≥ 4 for ADHD
- No lifetime history of DSM-5 bipolar disorder, psychotic disorder, pervasive developmental disorder, obsessive-compulsive disorder, substance abuse, or substance dependence (except nicotine) as assessed with the Mini-International Neuropsychiatric Interview (MINI)
- Able in the opinion of the investigator to complete all required study procedures.
Exclusion Criteria
- History of diagnosis of childhood disorder other than ADHD (e.g. autism, dyslexia)
- History of any general medical condition likely to require chronic use of medication with identified Central Nervous System (CNS) effects suspected to alter cognitive performance
- History of seizure disorder, brain tumor, other major neurological disorder or head injury resulting in loss of consciousness
- Serious oxygen deprivation
- Current psychopathology requiring ongoing treatment with antipsychotic medications, mood stabilizers, benzodiazepines, or anticonvulsants
- Current untreated psychopathology which is rated to be primary in terms of severity (greater than ADHD severity)
- Current treatment with guanfacine.
Data sourced from ClinicalTrials.gov (NCT02489279). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.