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N/A N=258 Randomized Quadruple-blind Prevention

Dorsal Penile Nerve Block for Rigid Cystoscopy in Men

Pain

Enrolled (actual)
258
Serious AEs
0.0%
Results posted
Jul 2016
Primary outcome: Primary: Visual Analog Scale (VAS) for Pain — 6; 4; 4 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Dorsal Penile Nerve Block (Procedure); Ropivacaine (Drug); Tetracaine (Drug)
Age
Adult, Older Adult · 20+ yrs
Sex
Male
Sponsor
West China Hospital
Primary completion
Mar 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Visual Analog Scale (VAS) for Pain
0; 0; 0
SECONDARY
Visual Analog Scale (VAS) for Pain
0; 0; 0
SECONDARY
Visual Analog Scale (VAS) for Pain
0; 0; 0
SECONDARY
Visual Analog Scale (VAS) for Pain
0; 0; 0
SECONDARY
Visual Analog Scale (VAS) for Pain
0; 0; 0
SECONDARY
Heart Rate Before Gel Administration
75.0; 75.9; 73.6
SECONDARY
Heart Rate at Cystoscopic Inspection of Penile and Bulbar Urthra
84.8; 83.8; 81.1
SECONDARY
Heart Rate at Cystoscopic Inspection of External Sphincter
96.7; 90.2; 86.2
SECONDARY
Heart Rate After Withdrawal of Cystoscope
76.7; 72.3; 71.6
SECONDARY
Mean Arterial Pressure Before Gel Administration
95.3; 96.6; 95.1
SECONDARY
Mean Arterial Pressure at Cystoscopic Inspection of Penile and Bulbar Urthra
100; 99.8; 98.2
SECONDARY
Mean Arterial Pressure at Cystoscopic Inspection of External Sphincter
113.7; 105.8; 104.8
SECONDARY
Mean Arterial Pressure After Withdrawal of Cystoscope
99.3; 95.7; 95.2
SECONDARY
Oxygen Saturation by Pulse Before Gel Administration
99; 98; 99
SECONDARY
Oxygen Saturation by Pulse at Cystoscopic Inspection of Penile and Bulbar Urthra
99; 98; 99
SECONDARY
Oxygen Saturation by Pulse at Cystoscopic Inspection of External Sphincter
99; 98; 99
SECONDARY
Oxygen Saturation by Pulse After Withdrawal of Cystoscope
99; 98; 99
SECONDARY
Breath Rate Before Gel Administration
19.8; 19.6; 19.5
SECONDARY
Breath Rate at Cystoscopic Inspection of Penile and Bulbar Urthra
20.0; 19.8; 19.6
SECONDARY
Breath Rate at Cystoscopic Inspection of External Sphincter
20.1; 19.8; 19.8
SECONDARY
Breath Rate After Withdrawal of Cystoscope
19.7; 19.4; 19.4

Summary

This study will determine the effectiveness and safety of dorsal penile nerve block (DPNB) in men undergoing rigid cystoscopy.

Eligibility Criteria

Inclusion Criteria

  • American Society of Anesthesiologists (ASA) Physical Status I-II
  • Without history of urethral or prostatic surgery
  • Without respiration or circulation disorders
  • Without chronic pain

Exclusion Criteria

  • Allergy to local anesthetics
  • Coagulation disorder or usage of antiplatelet drugs
  • Infection at the site of puncture point
  • Severe urethral stenosis
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02502487). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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