N/A
N=1,600
Regional Versus General Anesthesia for Promoting Independence After Hip Fracture
Hip Fractures
Bottom Line
View on ClinicalTrials.gov: NCT02507505 ↗Enrolled (actual)
1,600
Serious AEs
31.1%
Results posted
May 2024
Primary outcome: Primary: Death or Inability to Walk 10 Feet or Across a Room Without Human Assistance — 132; 132 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Regional Anesthesia (Procedure); General Anesthesia (Procedure)
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- University of Pennsylvania
- Primary completion
- Jun 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Death or Inability to Walk 10 Feet or Across a Room Without Human Assistance |
132; 132 | — |
| SECONDARY Overall Health and Disability |
22.7; 18.2; 10.4; 10.4; 10.4; 8.3 | — |
| SECONDARY Ability to Return to Home |
108; 114; 103; 90; 119; 116 | — |
| SECONDARY Chronic Pain |
4.5; 4.2; 3.5; 3.4; 3.1; 3.2 | — |
| SECONDARY Cognitive Function |
2; 2; 2; 2; 2; 2 | — |
| SECONDARY All-cause Mortality |
30; 32; 69; 63; 98; 92 | — |
| SECONDARY Need for Assistive Devices for Walking |
403; 397; 231; 231; 196; 193 | — |
| SECONDARY Acute Postoperative Pain |
7.9; 7.6; 7.1; 7.1; 6.8; 6.6 | — |
| SECONDARY Satisfaction With Care |
85; 97 | — |
| SECONDARY Postoperative Delirium |
130; 124 | — |
| SECONDARY Inpatient Mortality |
5; 13 | — |
| SECONDARY Major Inpatient Morbidity |
98; 120 | — |
Summary
The purpose of this study is to find out if two types of standard care anesthesia are the same or if one is better for people who have hip fractures.
Eligibility Criteria
Inclusion Criteria
- Clinically or radiographically diagnosed intracapsular or extracapsular hip fracture
- Planned surgical treatment via hemiarthroplasty, total hip arthroplasty or appropriate fixation procedure
- Ability to walk 10 feet or across a room without human assistance before fracture
Exclusion Criteria
- Planned concurrent surgery not amenable to spinal anesthesia
- Absolute contraindications to spinal anesthesia
- Periprosthetic fracture
Data sourced from ClinicalTrials.gov (NCT02507505). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.