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N/A N=80 Randomized Double-blind Prevention

Purge Vs no Purge in Living Donor Liver Transplantation Recipients

Ischemia Reperfusion Injury

Enrolled (actual)
80
Serious AEs
8.8%
Results posted
Oct 2015
Primary outcome: Primary: Lowest 5 Minutes Post-reperfusion Mean Arterial Blood Pressure — 66.03; 57.75 mmHg

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Purge (Procedure)
Age
Adult · 18+ yrs
Sex
All
Sponsor
Mansoura University
Primary completion
May 2014

Outcome Measures

OutcomeResultp-value
PRIMARY
Lowest 5 Minutes Post-reperfusion Mean Arterial Blood Pressure
66.03; 57.75
SECONDARY
Biliary Complications (Participants)
10; 6
SECONDARY
Ischemia Reperfusion Injury
3; 2
SECONDARY
Post-operative Infectious Complications
9; 8
SECONDARY
3 Months Mortality
4; 3

Summary

The investigators tested the impact of purging the graft contents and mesenteric blood into the systemic circulation versus washing out this volume out of the circulation in living donor liver transplantation recipients.

Eligibility Criteria

Inclusion Criteria

  • Adult living donor liver transplantation recipients of either sex in mansoura liver transplantation program

Exclusion Criteria

  • re-transplantation
  • Previous upper abdominal operation
  • Budd Chiari syndrome
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02540447). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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