Narrative review explores metformin and trimetazidine in cardiovascular conditions
The Hidden Cell Death Process Quietly Driving Heart Disease
This narrative review examines the roles of metformin and trimetazidine in cardiovascular diseases, atherosclerosis, vascular calcification,…
A specific type of cell death driven by iron and fat damage plays a key role in multiple heart conditions, including heart failure and ather…
Natural and synthetic compounds suppress inflammasome activation in NLRP3-driven pathologies
Your body has a built-in alarm system. It wakes up when you get a sore throat or a fever. But sometimes, this alarm gets stuck in the "on" position. That stuck alarm causes chronic pain and swelling. Scientists are finally learning how to turn it off.
This systematic review examined molecular mechanisms involving natural compounds like oridonin and pristimerin, alongside synthetic inhibito…
A hidden protein key inside your cells triggers the stuck alarm that causes chronic pain and swelling, and scientists now know how to stop i…
Systematic review links immune cell metabolic remodeling to outcomes in liver transplant recipients
Could immune cell energy shifts hold the key to better liver transplant survival?
A systematic review synthesizes evidence on immunometabolic remodeling in liver transplant recipients. It reports that dynamic adaptive chan…
Immune cell energy shifts after liver transplants determine rejection, injury, and tolerance, improving long-term survival, a new analysis f…
Review analyzes PANoptosis mechanisms and potential treatments for ischemia-reperfusion injury
Review explores a new cell death process in organ damage after blood flow returns
A systematic review analyzed the concept, molecular mechanisms, and potential treatment strategies targeting PANoptosis in ischemia-reperfus…
A new cell death process called PANoptosis drives organ damage when blood flow returns after a blockage, offering fresh targets for future t…