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Phase 3 Completed N=349 Randomized Single-blind Treatment

Does Endometrial Injury Improve Intrauterine Insemination Outcome?

Source: ClinicalTrials.gov NCT02542280 ↗
Enrolled (actual)
349
Serious AEs
0.0%
Results posted
Jan 2016
Primary outcomePrimary: Chemical Pregnancy Rate — 40; 19 participants

Summary

The investigator suggests that local endometrial injury using pipelle catheter performed in the follicular phase (cycle day 5, 6 or 7) of the stimulation cycle may improve the pregnancy rates among patients undergoing intrauterine insemination.

Outcome Measures

OutcomeResultp-value
PRIMARY
Chemical Pregnancy Rate
40; 19
PRIMARY
Clinical Pregnancy Rate
32; 13

Eligibility Criteria

Inclusion Criteria

  • 18 - 38 years.
  • patent fallopian tunes.
  • mild male factor.
  • anovulation.
  • unexplained infertility.

Exclusion Criteria

  • indications for ICSI.
  • evidence of pelvic inflammatory disease.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02542280). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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