N/A
Completed N=18
Image Guided Adaptive Radiotherapy in the Head-and-neck Region
Source: ClinicalTrials.gov NCT02545322 ↗Enrolled (actual)
18
Serious AEs
0.0%
Results posted
Apr 2017
Primary outcomePrimary: Planning Target Volume (PTV) Coverage Parameter D98% — 7 participants
Summary
Aim of this study is the clinical evaluation of an image-guided adaptive radiotherapy concept. This involves the adaption of the radiotherapy treatment plan according to changes in tissues and variations in patients position and posture during a radiotherapy treatment course, based on repeat CT scans.
It is investigated, if dosimetric improvements can be achieved using this approach and if the method using the software-package "ReDeform" can be implemented in clinical Routine.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Planning Target Volume (PTV) Coverage Parameter D98% |
7 | — |
| SECONDARY Volumetric Changes |
-4.3 | — |
Eligibility Criteria
Inclusion Criteria
- Patients with histo-pathologically verified malignancies in the head-and-neck without clinical signs of dissemination, who consented in radiotherapy or radio-chemotherapy.
Exclusion Criteria
- previous radiation therapy for head-and-neck
Data sourced from ClinicalTrials.gov (NCT02545322). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.