Pre-treatment body composition and acute kidney disease risk in head and neck cancer patients treated with cisplatin
Body composition may link to kidney issues in cancer patients
This prospective, monocentric, observational study of 110 patients with locally advanced head and neck cancer found that acute kidney diseas…
Low muscle mass and low lymphocyte counts may be linked to kidney disease risk during head and neck cancer treatment.
Preclinical deep learning framework shows improved dose prediction for unseen cancer sites
A Heavy Burden on Doctors
This is a preclinical development study of a deep learning framework for radiotherapy dose prediction. The framework performed comparably to…
A new AI tool can plan radiation doses for many different cancers at once.
Phase III trial indicates ultra-low-dose nivolumab may improve survival over chemotherapy in advanced solid tumors
A Tiny Dose of This Cancer Drug Is Outperforming Chemo
This Phase III randomized trial evaluated ultra-low-dose nivolumab against standard chemotherapy in patients with advanced solid tumors prog…
Giving a much smaller dose of a powerful cancer drug can extend life with fewer side effects, making treatment more tolerable and accessible…
Exercise improves functional capacity and quality of life in head and neck cancer survivors
Can exercise help head and neck cancer survivors walk farther and feel better?
A systematic review and meta-analysis of low-quality studies in head and neck cancer survivors found exercise was associated with improved f…
Head and neck cancer survivors who exercised walked nearly 100 meters farther, moved with more flexibility, and reported better quality of l…
Topical dexamethasone mouthwash reduces oral mucositis severity in head and neck cancer radiotherapy patients
Can a simple mouthwash prevent the painful mouth sores of cancer radiation?
A phase II randomized controlled trial of 50 patients with head and neck cancer receiving ≥60 Gy radiotherapy found prophylactic topical dex…
Rinsing with a steroid mouthwash during head and neck cancer radiation reduced severe mouth sores, delayed pain peaks, and prevented the wor…
Regional motif diversity score in cfDNA predicts pembrolizumab response in head and neck cancer
Can a DNA pattern predict who will heal from head and neck cancer immunotherapy?
A phase II trial in 68 patients with locally advanced, resectable HNSCC found that a regional motif diversity score (rMDS) in cell-free DNA …
A new DNA pattern in blood can reliably predict which head and neck cancer patients will respond to immunotherapy and live longer without th…
Green tea mouth rinse improved oral health scores but not pain or QOL in advanced head and neck cancer patients
Green tea mouth rinse improved oral health in advanced head and neck cancer patients
A 64-patient RCT in palliative care found that adding a green tea-based mouth rinse to usual care significantly improved oral health assessm…
A green tea mouth rinse improved oral health scores for advanced head and neck cancer patients over six weeks, though it did not reduce pain…
Photobiomodulation reduces severe oral mucositis (RR 0.46) and pain (RR 0.35) in head and neck cancer patients
Can light therapy ease the brutal mouth sores and pain of head and neck cancer treatment? A review of 30 studies suggests it can.
A meta-analysis of 30 RCTs (n=1748) found photobiomodulation significantly reduced the risk of severe oral mucositis (RR 0.46, 95% CI: 0.29-…
A review of 30 studies shows light therapy significantly reduces severe mouth sores and pain for head and neck cancer patients while improvi…