Egg consumption associated with reduced glioma risk in Eastern populations and increased head and neck cancer risk
Egg consumption shows mixed links to glioma and head and neck cancer
This meta-analysis of observational studies involving 1,274,437 participants found that egg consumption was associated with a reduced risk o…
New data shows a link between egg consumption and lower glioma risk in some groups, but a potential link to higher head and neck cancer risk…
Radiation therapy and nasopharyngeal cancer significantly increase risk of chronic rhinosinusitis in head and neck cancer patients
Head and neck cancer treatments may increase risk of sinus issues
This meta-analysis of 3685 patients identifies a 0.37 pooled incidence of chronic rhinosinusitis in head and neck cancer patients. The analy…
Patients with head and neck cancers face a higher risk of developing chronic sinus inflammation, especially after radiation therapy.
Radiotherapy for nasopharyngeal carcinoma is associated with a significant increased risk of otitis media with effusion
Radiotherapy for nasopharyngeal cancer increases risk of middle ear fluid
This meta-analysis of 582 patients indicates that radiotherapy for nasopharyngeal carcinoma is associated with a significant increase in oti…
Patients undergoing radiotherapy for nasopharyngeal cancer face a higher risk of developing fluid in the middle ear, a common side effect of…
IMRT plus cetuximab does not improve quality of life compared to IMRT plus cisplatin
Trial compares cetuximab and cisplatin for oropharyngeal cancer quality of life
This Phase III randomized controlled trial of 375 patients with p16+ oropharyngeal cancer found no significant difference in quality of life…
A clinical trial found that replacing cisplatin with cetuximab did not improve quality of life or swallowing for patients with oropharyngeal…
Preoperatively detected PTEN alterations in thyroid nodules correlate with a 32.4% risk of invasive malignancy
Molecular testing helps identify risk in thyroid nodules
This meta-analysis of 87 patients with Bethesda III/IV thyroid nodules identifies a 32.4% risk of invasive malignancy in those with preopera…
New molecular testing can help doctors identify the risk of cancer in thyroid nodules, providing a clearer picture for patients with uncerta…
Submental Artery Island Flap Shows 16% Pooled Locoregional Recurrence in Oral Cavity Reconstruction
Submental artery island flap is a safe option for oral cancer
This meta-analysis pooled data on the submental artery island flap (SAIF) for oral cavity defects after oral squamous cell carcinoma resecti…
A specific surgical technique called the submental artery island flap shows a low recurrence rate for patients with oral cavity defects.
Gut Microbiome and Metabolites May Modulate Thyroid Cancer Immunity and Treatment Response
Gut bacteria and metabolites may influence thyroid cancer treatment
This narrative review examines how gut dysbiosis, bacterial outer membrane components such as lipopolysaccharides, and metabolites including…
Your gut health might play a hidden role in how your body responds to thyroid cancer treatments and immune system interactions.
Empowered Survivor digital tool boosts self-efficacy in oral cancer survivors
Digital Intervention Improves Self-Care for Oral Cancer Survivors
In a randomized trial of 643 oral/oropharyngeal cancer survivors, the Empowered Survivor digital intervention improved self-efficacy at 2 an…
A new digital program helps oral cancer patients feel more confident and perform more self-care activities like swallowing and mobility exer…
CEUS combined with AI or elastography improves diagnostic performance for malignant thyroid nodules
Contrast-Enhanced Ultrasound Shows Promise for Identifying Thyroid Nodules
This network meta-analysis of 5022 thyroid nodules evaluated the diagnostic performance of contrast-enhanced ultrasound (CEUS) combined with…
New analysis shows that combining contrast-enhanced ultrasound with other imaging tools can help doctors better identify malignant thyroid n…
Impact of Perineural Invasion on Survival Outcomes in Oral Squamous Cell Carcinoma
Perineural invasion linked to poorer outcomes in oral squamous cell carcinoma
A meta-analysis of 23,580 patients confirms that perineural invasion is a potent independent predictor of poor survival and high recurrence …
A large review of over 23,000 patients shows that cancer cells spreading along nerves are linked to higher recurrence and lower survival rat…
Cetuximab-based regimens achieve 47% objective response rate in HNSCC after immune checkpoint inhibitor failure
Cetuximab shows activity for head and neck cancer patients
This meta-analysis evaluates cetuximab-based regimens for patients with recurrent or metastatic head and neck squamous cell carcinoma follow…
New data shows cetuximab-based treatments provide meaningful results for head and neck cancer patients after other treatments fail.
Higher pretreatment HALP score is associated with improved overall survival in head and neck cancer
Higher HALP scores linked to better survival in head cancer
This meta-analysis of 1759 patients found that a higher pretreatment HALP score is associated with improved overall survival (95% CI 0.41-0.…
A new analysis shows that a specific blood score can help doctors predict survival outcomes for patients with head and neck cancer.
Research across Cancer
Related studies from across the Cancer family.
Narrative review covers diagnostic and treatment strategies for metastatic head and neck cancer with no identifiable primary tumor
Doctors use many tools to treat head and neck cancer when the main tumor is hidden
This narrative review addresses diagnostic and treatment strategies for metastatic cases of head and neck cancer with no identifiable primar…
When head and neck cancer spreads but the original spot is missing, doctors use many tools. Imaging, special tests, and surgery help find th…
SABR Protocol Deviations Linked to Poorer Survival in Oligometastatic Head and Neck Cancer
Major protocol deviations cut survival time for head and neck cancer patients
This exploratory analysis of a randomized phase 2 trial (GORTEC 2014-04) in 69 patients with oligometastatic head and neck cancer found that…
Strict radiation quality checks linked to better survival for head and neck cancer patients. Minor or major errors during treatment reduced …
In a prospective cohort, periampullary tumor surgery affected quality of life and survival metrics
Life After Major Cancer Surgery Isn’t What We Thought
This prospective cohort study evaluated 111 patients undergoing pancreaticoduodenectomy for periampullary tumors at a University Medical Cen…
Imagine waking up after major cancer surgery.
Case report suggests grade 3 ICI-induced inflammatory arthritis may correlate with sustained response to tislelizumab in advanced head and neck carcinoma
Could a painful joint flare actually signal that cancer treatment is working long-term?
This case report and literature review describes a single patient with advanced unknown primary carcinoma of the head and neck receiving mai…
A patient with advanced head and neck cancer stayed in complete remission for over a year after joint pain from treatment forced doctors to …
Questions about Head and Neck Cancer
What is the risk of acute kidney disease for head and neck cancer patients treated with cisplatin?
Cisplatin-based chemoradiotherapy in head and neck cancer carries a high risk of acute kidney injury, with reported incidences ranging from 20% to 69% depending on the cisplatin regimen and patient factors.
Full answer →All Head and Neck Cancer Articles
- IMRT plus cetuximab does not improve quality of life compared to IMRT plus cisplatin
- Submental Artery Island Flap Shows 16% Pooled Locoregional Recurrence in Oral Cavity Reconstruction
- Radiation therapy and nasopharyngeal cancer significantly increase risk of chronic rhinosinusitis in head and neck cancer patients
- Preoperatively detected PTEN alterations in thyroid nodules correlate with a 32.4% risk of invasive malignancy
- Radiotherapy for nasopharyngeal carcinoma is associated with a significant increased risk of otitis media with effusion
- Egg consumption associated with reduced glioma risk in Eastern populations and increased head and neck cancer risk
- Gut Microbiome and Metabolites May Modulate Thyroid Cancer Immunity and Treatment Response
- Empowered Survivor digital tool boosts self-efficacy in oral cancer survivors
- CEUS combined with AI or elastography improves diagnostic performance for malignant thyroid nodules
- Impact of Perineural Invasion on Survival Outcomes in Oral Squamous Cell Carcinoma
- Cetuximab-based regimens achieve 47% objective response rate in HNSCC after immune checkpoint inhibitor failure
- Higher pretreatment HALP score is associated with improved overall survival in head and neck cancer
- AI-based MRI shows 0.82 AUC for detecting cervical lymph node metastases in oral squamous cell carcinoma
- Immune cell-based therapy shows no significant benefits for tumor response or survival in HNSCC trials
- Volumetric inaccuracies in nasopharyngeal carcinoma primary tumor segmentation may reduce tumor control probability
- C3-derived skeletal muscle index shows strong correlation with L3 index in head and neck cancer
- HPV16 constitutes 92.5% of single infections in oropharyngeal squamous cell carcinoma cases
- Perioperative and postoperative immunotherapy timing determines clinical outcomes in locally advanced head and neck squamous cell carcinoma
- Hashimoto's thyroiditis is a risk factor for papillary thyroid cancer with associated improved outcomes
- Higher preoperative neutrophil-to-lymphocyte ratio predicts poorer survival in oral squamous cell carcinoma patients
- ALC decline greater than 0.74x10^9/L independently predicts poorer OS and PFS in LA-HNSCC
- Small bowel metastasis from esophageal squamous cell carcinoma shows male predominance and 6-month median survival
- Genomic instability markers show associations with malignant transformation in oral leukoplakias and proliferative verrucous leukaplakias
- Malnutrition and sarcopenia are associated with poorer treatment tolerance and higher toxicity in head and neck cancer
- Paclitaxel and Cisplatin Combination Improves Outcomes in Locoregionally Advanced Nasopharyngeal Carcinoma
- Deep Learning algorithms demonstrate potential for diagnosing oral potentially malignant disorders and squamous cell carcinoma
- Plectin knockdown and troglitazone treatment inhibit growth and migration in papillary thyroid carcinoma cell lines
- Sociodemographic, laboratory, and ultrasonographic factors are associated with malignancy risk in thyroid nodules
- PD-1/PD-L1 inhibitors provide superior overall survival compared to chemotherapy or cetuximab in platinum-refractory HNSCC
- Toripalimab plus paclitaxel and cisplatin improves overall survival in advanced esophageal squamous-cell carcinoma
- Intraoperative frozen section shows 98.8% specificity but limited sensitivity for detecting malignancy in Bethesda III nodules
- Ninjin’yoeito attenuates postoperative Prognostic Nutritional Index decline in patients with oral squamous cell carcinoma
- Post-radiotherapy dental extractions increase odds of osteoradionecrosis by 8.38 in head and neck cancer patients
- High NLRP-3 Expression Linked to Poor Survival in Solid Cancers
- TORS yields oncologic outcomes comparable to radiotherapy in early-stage oropharyngeal cancer
- Sarcopenia triples dysphagia odds across cancers, meta-analysis finds
- Circulating miRNAs show high diagnostic accuracy for oral squamous cell carcinoma with AUC of approximately 0.90
- Molecular drivers including DNA damage response and epigenetics contribute to treatment resistance in HPV-positive OPSCC
- Postoperative radiotherapy improves survival and reduces recurrence in resected ESCC
- Occupational exposure to asbestos-free talc does not support increased risk of lung or laryngeal cancers
- Pretreatment sarcopenia and low PNI are associated with worse survival in ICI-treated HNSCC
- No established correlation exists between paragangliomas and cervical lymph node metastasis in papillary thyroid carcinoma
- Immunonutrition may improve management of radiation-induced oral mucositis in head and neck cancer patients
- Lenvatinib plus pembrolizumab did not improve overall survival compared to standard of care
- Postoperative radiotherapy reduces local and peristomal recurrence rates in laryngeal cancer patients with preoperative tracheotomy
- Camrelizumab and apatinib show higher response rates and survival in treatment-naive patients with ESCC
- Combination Therapies Improve Progression Free Survival in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
- Zygomatic implants provide high survival rates for maxillary reconstruction in head and neck cancer patients
- High tumor mutational burden correlates with improved objective response rate in HNSCC patients
- FNA-Tg and BRAF V600E analysis can rectify histopathological misdiagnosis of cervical lymph node metastasis
- Sintilimab may trigger autoimmune GFAP astrocytopathy in esophageal squamous cell carcinoma patients
- HPV shows strong association with oropharyngeal SCC while other oncogenic viruses show limited evidence
- Prophylactic PEG tube placement improves nutritional status and reduces hospitalizations for head and neck cancer patients
- Neoadjuvant chemoimmunotherapy improves pathological response and surgical rates in resectable esophageal squamous cell carcinoma
- Hyperspectral imaging shows strong diagnostic performance for oral cancer detection in scoping review
- Contrast-enhanced ultrasound shows 81.6% diagnostic accuracy for differentiating benign from malignant thyroid nodules
- Early recognition of femoral metastasis in HNSCC is essential to facilitate timely palliative intervention
- Pretreatment CPS and HPV status correlate with pathological response in neoadjuvant immunotherapy for LAHNSCC
- Primary endoscopic nasopharyngectomy achieves 90.6% five-year overall survival across all tumor stages in nasopharyngeal carcinoma
- High PTTG1 expression correlates with poorer survival and advanced disease in various solid tumors
- Zinc supplementation shows potential in reducing severe radiation-induced oral mucositis in head and neck cancer patients
- Oral diseases stem from disrupted host-microbiome-immune balance, narrative review argues
- Anti-PD-1 based chemo-immunotherapy for nasopharyngeal carcinoma yields objective response rates of 20 to 91 percent
- HOX gene dysregulation influences cellular processes but currently lacks utility as reliable HNSCC biomarkers
- PD-1 inhibitors plus chemotherapy achieve 64% objective response rate in recurrent or metastatic nasopharyngeal carcinoma
- Advanced experimental models and computational tools provide dynamic frameworks for understanding oral disease progression
- Microbial metabolites may promote or suppress cancer progression through inflammation, DNA damage, or immune modulation
- Fianlimab plus cemiplimab showed objective response rates of 20% to 33% in advanced solid tumors during a Phase 1 study.
- Local brain therapies associated with reduced mortality in HNSCC patients with brain metastasis
- Molecular markers may improve risk assessment in oral potentially malignant disorders
- Radiotherapy and chemotherapy show no clear link to obstructive sleep apnea in head and neck cancer patients
- Aspiration pneumonia affects 74.8% of head and neck cancer patients after chemoradiotherapy
- 20-fraction hypofractionated radiotherapy passes noninferiority for tumor control and late toxicity in locally advanced head and neck cancer
- Robot-assisted oesophagectomy shows non-inferior survival in oesophageal squamous cell carcinoma
- Transitioning from static TNM staging to a multidimensional, adaptive treatment model integrating genomics and immunology for HPV-associated OPSCC
- Immune checkpoint blockade shows promise but faces resistance challenges in nasopharyngeal carcinoma
- Scoping review of AI for head and neck cancer risk stratification
- Case report review highlights suspicion of breast cancer metastasis to thyroid in a 54-year-old woman
- Narrative review covers diagnostic and treatment strategies for metastatic head and neck cancer with no identifiable primary tumor
- Evidence mapping review on nutritional prehabilitation for head and neck cancer patients
- Case report and review: IVIg and efgartigimod in Guillain-Barré with Graves disease and thyroid cancer
- Systematic review and meta-analysis on immunotherapy for head and neck squamous cell carcinoma
- FDA approves OPDIVO QVANTIG for multiple advanced cancer indications including renal cell carcinoma and melanoma
- Meta-analysis finds sex-based differences in ICI survival benefit for advanced gastroesophageal cancer
- Systematic review and meta-analysis of ML with cfDNA for cancer detection across stages
- Narrative review explores mitochondrial-targeted therapeutics for oral squamous cell carcinoma
- Review of 32 cases of thyroid hemiagenesis with carcinoma highlights surgical and diagnostic patterns
- Oropharyngeal cancer radiotherapy protocols show improved patient-reported outcomes over time
- Meta-analysis finds BCI_net prognostic for overall survival in oral squamous cell carcinoma
- Review links mature intra-tumoral TLS to better prognosis and immunotherapy response in head and neck cancer
- Narrative review on therapeutic cancer vaccines for head and neck squamous cell carcinoma
- Narrative review explores Veillonella's dynamic role in oral squamous cell carcinoma
- Meta-analysis of postoperative radiotherapy versus radiochemotherapy for salivary gland cancer finds no significant survival difference
- Review of epigenetic dysregulation in nasopharyngeal carcinoma management
- Early time-of-day immune checkpoint inhibitor administration improves overall survival in advanced solid tumors
- Meta-analysis shows neoadjuvant chemoradiation improves resection and survival outcomes for esophageal squamous cell carcinoma patients compared to chemotherapy alone
- Narrative review discusses HPV-associated head and neck and cervical squamous cell carcinoma without reporting specific outcomes
- Review of multimodal deep learning model for esophageal squamous cell carcinoma diagnosis
- SABR Protocol Deviations Linked to Poorer Survival in Oligometastatic Head and Neck Cancer
- Lignocaine-based opioid-free anesthesia increases sevoflurane need in head-and-neck cancer surgery
- SIB-RT plus S-1 improves survival in elderly inoperable esophageal cancer
- GERD Associated with Increased Risk of Laryngeal Cancer in Meta-Analysis
- Meta-analysis finds frozen section reliable for tumor-free margins in OSCC
- Review of PBMC processing conditions in head and neck squamous cell carcinoma treatment-naive patients
- Narrative review discusses targeting ferroptosis and cuproptosis in oral squamous cell carcinoma
- Pre-treatment body composition and acute kidney disease risk in head and neck cancer patients treated with cisplatin
- Comprehensive salivary gland–sparing helical tomotherapy reduces radiation-induced xerostomia in nasopharyngeal carcinoma patients
- Machine learning model predicts central lymph node metastasis in papillary thyroid carcinoma
- Deep learning segmentation with CT elasticity features predicts right recurrent laryngeal nerve metastasis in esophageal cancer
- Iron and oxidative stress biomarkers linked to oral cancer recurrence after surgery
- TIRADS and Bethesda systems predict thyroid malignancy in 70 patients at Baghdad Teaching Hospital
- Preclinical deep learning framework shows improved dose prediction for unseen cancer sites
- Neoadjuvant Chemoimmunotherapy Alters Tumor Microenvironment in Esophageal Cancer
- Case series describes four clear cell variant papillary thyroid carcinoma cases with NCOA4-RET fusions
- Personalized swallowing rehab improves outcomes after oral cancer surgery
- Phase III trial indicates ultra-low-dose nivolumab may improve survival over chemotherapy in advanced solid tumors
- Nomogram model using NLR, age, and ultrasound features discriminates papillary thyroid carcinoma from benign nodules
- High NSUN3 expression linked to poor survival in oral squamous cell carcinoma
- Meta-analysis of oxidative stress markers in oral leukoplakia versus healthy controls
- EBNA1 SeroStrip-HT shows high accuracy for nasopharyngeal carcinoma risk assessment in a nested case-control study
- Autopsy study finds 55% thyroid nodular disease prevalence in Mexico City hospital patients
- Becotatug vedotin shows 20.9% objective response in recurrent head and neck squamous cell carcinoma after prior therapy
- Meta-analysis of 7,750 saliva samples validates non-invasive disease prediction models for nasopharyngeal carcinoma, colorectal cancer, and PLHIV
- Mini review examines genetic polymorphisms and viral markers linked to nasopharyngeal carcinoma risk
- Classification framework shows 79% to 98% performance for oral squamous cell carcinoma on histopathological images
- Review links oral microbiome dysbiosis to malignant transformation in oral lichen planus
- Radiotherapy de-escalation strategies show reduced toxicity but modest clinical benefits in head and neck cancer cohorts
- Phase 1b ABBV-368 combinations in recurrent/metastatic HNSCC show 14.3% overall response rate
- Timing of surgery after neoadjuvant chemoimmunotherapy impacts survival in operable esophageal squamous cell carcinoma
- Intravenous vitamin C did not reduce gastrointestinal toxicities but attenuated platelet decline in nasopharyngeal carcinoma patients
- Phase 3 trial compares IMPT versus IMRT plus cisplatin in locally advanced oropharyngeal squamous cell carcinoma
- Low OT-NLR predicts superior survival in recurrent/metastatic HNSCC treated with cetuximab plus nivolumab
- Penpulimab plus chemotherapy significantly improved progression-free survival in recurrent or metastatic nasopharyngeal carcinoma
- Anti-PD-1 plus chemoradiotherapy improved event-free survival in MS1 subtype nasopharyngeal carcinoma patients compared with chemoradiotherapy alone
- Frozen visual encoders compared for thyroid nodule classification in the ThyroidEffi 1.0 dataset
- Becotatug vedotin shows antitumor activity in pretreated recurrent or metastatic nasopharyngeal carcinoma
- Systematic review finds serum biomarkers show variable diagnostic accuracy for oral cancer detection
- MRLN sparing radiotherapy shows non-inferior survival, reduced toxicity in nasopharyngeal carcinoma
- Breg-related gene signature predicts survival and immune landscape in head and neck squamous cell carcinoma
- Sedentary time, insomnia, and weight linked to high-risk thyroid nodules in retrospective cohort
- BRAFV600E mutation testing shows diagnostic value in high-suspicion thyroid nodules with non-malignant cytology
- Topical dexamethasone mouthwash reduces oral mucositis severity in head and neck cancer radiotherapy patients
- Exercise improves functional capacity and quality of life in head and neck cancer survivors
- Regional motif diversity score in cfDNA predicts pembrolizumab response in head and neck cancer
- Deep learning model using preoperative CT predicts lymph node metastasis in papillary thyroid carcinoma
- TyG-BMI index shows positive association with papillary thyroid carcinoma odds in Chinese cohort
- Green tea mouth rinse improved oral health scores but not pain or QOL in advanced head and neck cancer patients
- Machine learning algorithm predicts skip metastasis in papillary thyroid cancer in retrospective cohort
- Meta-analysis finds Qi-deficiency constitution most prevalent in nasopharyngeal carcinoma health states
- Phase 3 trial compares pembrolizumab with or without lenvatinib in PD-L1+ recurrent/metastatic HNSCC
- PD-1 inhibitors + chemo improve OS, PFS, ORR in first-line advanced ESCC; benefit limited in PD-L1 CPS <1
- Meta-analysis: PD-1/PD-L1 inhibitors show 45% ORR, 16.27-month median OS in recurrent/metastatic NPC
- Photobiomodulation reduces severe oral mucositis (RR 0.46) and pain (RR 0.35) in head and neck cancer patients