No established correlation exists between paragangliomas and cervical lymph node metastasis in papillary thyroid carcinoma
Distinguishing Between Thyroid Cancer and Paraganglioma for Better Diagnosis
This case report and literature review examines the relationship between paragangliomas and cervical lymph node metastasis in patients with …
Doctors must accurately distinguish between thyroid cancer and paragangliomas to ensure correct treatment plans and accurate patient prognos…
Immunonutrition may improve management of radiation-induced oral mucositis in head and neck cancer patients
Immunonutrition may help manage mouth sores in head and neck cancer
This narrative review examines the role of immunonutrition for managing oral mucositis in patients with head and neck malignancies undergoin…
Patients with head and neck cancer often suffer from painful mouth sores. New evidence suggests immunonutrition could help manage these symp…
Lenvatinib plus pembrolizumab did not improve overall survival compared to standard of care
Trial shows lenvatinib and pembrolizumab do not improve survival
This Phase 2 randomized trial evaluated lenvatinib and pembrolizumab in 374 adults with recurrent or metastatic head and neck squamous cell …
A Phase 2 trial found that a combination of lenvatinib and pembrolizumab did not improve overall survival for patients with advanced head an…
High tumor mutational burden correlates with improved objective response rate in HNSCC patients
High tumor mutation burden predicts better results in head cancer
This meta-analysis of 1472 patients with head and neck squamous cell carcinoma (HNSCC) found that high tumor mutational burden (TMB) is asso…
A high number of mutations in a tumor may help doctors predict which patients will respond best to immunotherapy.
Combination Therapies Improve Progression Free Survival in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Combination therapies show promise for advanced head and neck cancer
This meta-analysis evaluated combination therapies involving targeted agents or immunotherapy with chemotherapy for patients with recurrent …
Combining immunotherapy or targeted drugs with chemotherapy may help patients with advanced head and neck cancer live longer without the dis…
Postoperative radiotherapy reduces local and peristomal recurrence rates in laryngeal cancer patients with preoperative tracheotomy
Radiotherapy May Lower Recurrence Risk After Laryngectomy for Cancer
This meta-analysis of 4339 patients evaluates the impact of postoperative radiotherapy (PORT) on recurrence rates following total laryngecto…
Postoperative radiotherapy may lower the risk of cancer returning in the throat area for patients who had a tracheotomy before surgery.
Camrelizumab and apatinib show higher response rates and survival in treatment-naive patients with ESCC
Treatment Naive Patients Show Better Survival with Camrelizumab and Apatinib
This meta-analysis evaluates the efficacy of camrelizumab plus apatinib for advanced or metastatic esophageal squamous cell carcinoma. The a…
Patients with advanced esophageal cancer who have not had prior treatment may see better survival rates when using a combination of camreliz…
Zygomatic implants provide high survival rates for maxillary reconstruction in head and neck cancer patients
Zygomatic implants show high survival for head and neck cancer
This systematic review and meta-analysis of 294 patients with extensive maxillary defects found a 97% overall implant survival rate. The ana…
New data shows zygomatic implants have a 97% survival rate, offering a reliable way to restore jaw function after cancer surgery.
Sintilimab may trigger autoimmune GFAP astrocytopathy in esophageal squamous cell carcinoma patients
New cancer treatment may cause rare brain inflammation in patients
This case report and literature review describes a patient with advanced esophageal squamous cell carcinoma who developed autoimmune GFAP as…
A new type of immunotherapy for esophageal cancer can trigger a rare brain condition, requiring doctors to watch for early signs of neurolog…
FNA-Tg and BRAF V600E analysis can rectify histopathological misdiagnosis of cervical lymph node metastasis
Combined Testing Corrects Diagnosis of Thyroid Cancer Lymph Node Spread
This case report describes a 52-year-old female with papillary thyroid carcinoma where combined FNA-Tg and BRAF V600E analysis corrected a h…
A new testing method using FNA-Tg and BRAF V600E analysis helped correctly identify cancer spread in a patient with thyroid cancer.
HPV shows strong association with oropharyngeal SCC while other oncogenic viruses show limited evidence
Viruses linked to oral and throat cancers in new review
This systematic review examines the role of various oncogenic viruses in oral and oropharyngeal squamous cell carcinomas. It identifies a co…
A strong link between HPV and throat cancer is confirmed, while other viruses show less clear evidence of causing cancer.
Prophylactic PEG tube placement improves nutritional status and reduces hospitalizations for head and neck cancer patients
Proactive Feeding Tubes May Improve Support for Head and Neck Cancer
This meta-analysis of 1279 patients evaluates prophylactic versus reactive percutaneous endoscopic gastrostomy (PEG) tubes in head and neck …
Early placement of feeding tubes may improve nutritional stability and reduce hospital stays for patients undergoing head and neck cancer tr…
Research across Cancer
Related studies from across the Cancer family.
Narrative review covers diagnostic and treatment strategies for metastatic head and neck cancer with no identifiable primary tumor
Doctors use many tools to treat head and neck cancer when the main tumor is hidden
This narrative review addresses diagnostic and treatment strategies for metastatic cases of head and neck cancer with no identifiable primar…
When head and neck cancer spreads but the original spot is missing, doctors use many tools. Imaging, special tests, and surgery help find th…
SABR Protocol Deviations Linked to Poorer Survival in Oligometastatic Head and Neck Cancer
Major protocol deviations cut survival time for head and neck cancer patients
This exploratory analysis of a randomized phase 2 trial (GORTEC 2014-04) in 69 patients with oligometastatic head and neck cancer found that…
Strict radiation quality checks linked to better survival for head and neck cancer patients. Minor or major errors during treatment reduced …
In a prospective cohort, periampullary tumor surgery affected quality of life and survival metrics
Life After Major Cancer Surgery Isn’t What We Thought
This prospective cohort study evaluated 111 patients undergoing pancreaticoduodenectomy for periampullary tumors at a University Medical Cen…
Imagine waking up after major cancer surgery.
Case report suggests grade 3 ICI-induced inflammatory arthritis may correlate with sustained response to tislelizumab in advanced head and neck carcinoma
Could a painful joint flare actually signal that cancer treatment is working long-term?
This case report and literature review describes a single patient with advanced unknown primary carcinoma of the head and neck receiving mai…
A patient with advanced head and neck cancer stayed in complete remission for over a year after joint pain from treatment forced doctors to …
Questions about Head and Neck Cancer
What is the risk of acute kidney disease for head and neck cancer patients treated with cisplatin?
Cisplatin-based chemoradiotherapy in head and neck cancer carries a high risk of acute kidney injury, with reported incidences ranging from 20% to 69% depending on the cisplatin regimen and patient factors.
Full answer →All Head and Neck Cancer Articles
- No established correlation exists between paragangliomas and cervical lymph node metastasis in papillary thyroid carcinoma
- Immunonutrition may improve management of radiation-induced oral mucositis in head and neck cancer patients
- Lenvatinib plus pembrolizumab did not improve overall survival compared to standard of care
- Postoperative radiotherapy reduces local and peristomal recurrence rates in laryngeal cancer patients with preoperative tracheotomy
- Camrelizumab and apatinib show higher response rates and survival in treatment-naive patients with ESCC
- Combination Therapies Improve Progression Free Survival in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
- Zygomatic implants provide high survival rates for maxillary reconstruction in head and neck cancer patients
- High tumor mutational burden correlates with improved objective response rate in HNSCC patients
- FNA-Tg and BRAF V600E analysis can rectify histopathological misdiagnosis of cervical lymph node metastasis
- Sintilimab may trigger autoimmune GFAP astrocytopathy in esophageal squamous cell carcinoma patients
- HPV shows strong association with oropharyngeal SCC while other oncogenic viruses show limited evidence
- Prophylactic PEG tube placement improves nutritional status and reduces hospitalizations for head and neck cancer patients
- Neoadjuvant chemoimmunotherapy improves pathological response and surgical rates in resectable esophageal squamous cell carcinoma
- Hyperspectral imaging shows strong diagnostic performance for oral cancer detection in scoping review
- Contrast-enhanced ultrasound shows 81.6% diagnostic accuracy for differentiating benign from malignant thyroid nodules
- Early recognition of femoral metastasis in HNSCC is essential to facilitate timely palliative intervention
- Pretreatment CPS and HPV status correlate with pathological response in neoadjuvant immunotherapy for LAHNSCC
- Primary endoscopic nasopharyngectomy achieves 90.6% five-year overall survival across all tumor stages in nasopharyngeal carcinoma
- High PTTG1 expression correlates with poorer survival and advanced disease in various solid tumors
- Zinc supplementation shows potential in reducing severe radiation-induced oral mucositis in head and neck cancer patients
- Oral diseases stem from disrupted host-microbiome-immune balance, narrative review argues
- Anti-PD-1 based chemo-immunotherapy for nasopharyngeal carcinoma yields objective response rates of 20 to 91 percent
- HOX gene dysregulation influences cellular processes but currently lacks utility as reliable HNSCC biomarkers
- PD-1 inhibitors plus chemotherapy achieve 64% objective response rate in recurrent or metastatic nasopharyngeal carcinoma
- Advanced experimental models and computational tools provide dynamic frameworks for understanding oral disease progression
- Microbial metabolites may promote or suppress cancer progression through inflammation, DNA damage, or immune modulation
- Fianlimab plus cemiplimab showed objective response rates of 20% to 33% in advanced solid tumors during a Phase 1 study.
- Local brain therapies associated with reduced mortality in HNSCC patients with brain metastasis
- Molecular markers may improve risk assessment in oral potentially malignant disorders
- Radiotherapy and chemotherapy show no clear link to obstructive sleep apnea in head and neck cancer patients
- Aspiration pneumonia affects 74.8% of head and neck cancer patients after chemoradiotherapy
- 20-fraction hypofractionated radiotherapy passes noninferiority for tumor control and late toxicity in locally advanced head and neck cancer
- Robot-assisted oesophagectomy shows non-inferior survival in oesophageal squamous cell carcinoma
- Transitioning from static TNM staging to a multidimensional, adaptive treatment model integrating genomics and immunology for HPV-associated OPSCC
- Immune checkpoint blockade shows promise but faces resistance challenges in nasopharyngeal carcinoma
- Scoping review of AI for head and neck cancer risk stratification
- Case report review highlights suspicion of breast cancer metastasis to thyroid in a 54-year-old woman
- Narrative review covers diagnostic and treatment strategies for metastatic head and neck cancer with no identifiable primary tumor
- Evidence mapping review on nutritional prehabilitation for head and neck cancer patients
- Case report and review: IVIg and efgartigimod in Guillain-Barré with Graves disease and thyroid cancer
- Systematic review and meta-analysis on immunotherapy for head and neck squamous cell carcinoma
- FDA approves OPDIVO QVANTIG for multiple advanced cancer indications including renal cell carcinoma and melanoma
- Meta-analysis finds sex-based differences in ICI survival benefit for advanced gastroesophageal cancer
- Systematic review and meta-analysis of ML with cfDNA for cancer detection across stages
- Narrative review explores mitochondrial-targeted therapeutics for oral squamous cell carcinoma
- Review of 32 cases of thyroid hemiagenesis with carcinoma highlights surgical and diagnostic patterns
- Oropharyngeal cancer radiotherapy protocols show improved patient-reported outcomes over time
- Meta-analysis finds BCI_net prognostic for overall survival in oral squamous cell carcinoma
- Review links mature intra-tumoral TLS to better prognosis and immunotherapy response in head and neck cancer
- Narrative review on therapeutic cancer vaccines for head and neck squamous cell carcinoma
- Narrative review explores Veillonella's dynamic role in oral squamous cell carcinoma
- Meta-analysis of postoperative radiotherapy versus radiochemotherapy for salivary gland cancer finds no significant survival difference
- Review of epigenetic dysregulation in nasopharyngeal carcinoma management
- Early time-of-day immune checkpoint inhibitor administration improves overall survival in advanced solid tumors
- Meta-analysis shows neoadjuvant chemoradiation improves resection and survival outcomes for esophageal squamous cell carcinoma patients compared to chemotherapy alone
- Narrative review discusses HPV-associated head and neck and cervical squamous cell carcinoma without reporting specific outcomes
- Review of multimodal deep learning model for esophageal squamous cell carcinoma diagnosis
- SABR Protocol Deviations Linked to Poorer Survival in Oligometastatic Head and Neck Cancer
- Lignocaine-based opioid-free anesthesia increases sevoflurane need in head-and-neck cancer surgery
- SIB-RT plus S-1 improves survival in elderly inoperable esophageal cancer
- GERD Associated with Increased Risk of Laryngeal Cancer in Meta-Analysis
- Meta-analysis finds frozen section reliable for tumor-free margins in OSCC
- Review of PBMC processing conditions in head and neck squamous cell carcinoma treatment-naive patients
- Narrative review discusses targeting ferroptosis and cuproptosis in oral squamous cell carcinoma
- Pre-treatment body composition and acute kidney disease risk in head and neck cancer patients treated with cisplatin
- Comprehensive salivary gland–sparing helical tomotherapy reduces radiation-induced xerostomia in nasopharyngeal carcinoma patients
- Machine learning model predicts central lymph node metastasis in papillary thyroid carcinoma
- Deep learning segmentation with CT elasticity features predicts right recurrent laryngeal nerve metastasis in esophageal cancer
- Iron and oxidative stress biomarkers linked to oral cancer recurrence after surgery
- TIRADS and Bethesda systems predict thyroid malignancy in 70 patients at Baghdad Teaching Hospital
- Preclinical deep learning framework shows improved dose prediction for unseen cancer sites
- Neoadjuvant Chemoimmunotherapy Alters Tumor Microenvironment in Esophageal Cancer
- Case series describes four clear cell variant papillary thyroid carcinoma cases with NCOA4-RET fusions
- Personalized swallowing rehab improves outcomes after oral cancer surgery
- Phase III trial indicates ultra-low-dose nivolumab may improve survival over chemotherapy in advanced solid tumors
- Nomogram model using NLR, age, and ultrasound features discriminates papillary thyroid carcinoma from benign nodules
- High NSUN3 expression linked to poor survival in oral squamous cell carcinoma
- Meta-analysis of oxidative stress markers in oral leukoplakia versus healthy controls
- EBNA1 SeroStrip-HT shows high accuracy for nasopharyngeal carcinoma risk assessment in a nested case-control study
- Autopsy study finds 55% thyroid nodular disease prevalence in Mexico City hospital patients
- Becotatug vedotin shows 20.9% objective response in recurrent head and neck squamous cell carcinoma after prior therapy
- Meta-analysis of 7,750 saliva samples validates non-invasive disease prediction models for nasopharyngeal carcinoma, colorectal cancer, and PLHIV
- Mini review examines genetic polymorphisms and viral markers linked to nasopharyngeal carcinoma risk
- Classification framework shows 79% to 98% performance for oral squamous cell carcinoma on histopathological images
- Review links oral microbiome dysbiosis to malignant transformation in oral lichen planus
- Radiotherapy de-escalation strategies show reduced toxicity but modest clinical benefits in head and neck cancer cohorts
- Phase 1b ABBV-368 combinations in recurrent/metastatic HNSCC show 14.3% overall response rate
- Timing of surgery after neoadjuvant chemoimmunotherapy impacts survival in operable esophageal squamous cell carcinoma
- Intravenous vitamin C did not reduce gastrointestinal toxicities but attenuated platelet decline in nasopharyngeal carcinoma patients
- Low OT-NLR predicts superior survival in recurrent/metastatic HNSCC treated with cetuximab plus nivolumab
- Phase 3 trial compares IMPT versus IMRT plus cisplatin in locally advanced oropharyngeal squamous cell carcinoma
- Anti-PD-1 plus chemoradiotherapy improved event-free survival in MS1 subtype nasopharyngeal carcinoma patients compared with chemoradiotherapy alone
- Penpulimab plus chemotherapy significantly improved progression-free survival in recurrent or metastatic nasopharyngeal carcinoma
- Frozen visual encoders compared for thyroid nodule classification in the ThyroidEffi 1.0 dataset
- Becotatug vedotin shows antitumor activity in pretreated recurrent or metastatic nasopharyngeal carcinoma
- Systematic review finds serum biomarkers show variable diagnostic accuracy for oral cancer detection
- MRLN sparing radiotherapy shows non-inferior survival, reduced toxicity in nasopharyngeal carcinoma
- Breg-related gene signature predicts survival and immune landscape in head and neck squamous cell carcinoma
- Sedentary time, insomnia, and weight linked to high-risk thyroid nodules in retrospective cohort
- BRAFV600E mutation testing shows diagnostic value in high-suspicion thyroid nodules with non-malignant cytology
- Topical dexamethasone mouthwash reduces oral mucositis severity in head and neck cancer radiotherapy patients
- Exercise improves functional capacity and quality of life in head and neck cancer survivors
- Regional motif diversity score in cfDNA predicts pembrolizumab response in head and neck cancer
- Deep learning model using preoperative CT predicts lymph node metastasis in papillary thyroid carcinoma
- TyG-BMI index shows positive association with papillary thyroid carcinoma odds in Chinese cohort
- Green tea mouth rinse improved oral health scores but not pain or QOL in advanced head and neck cancer patients
- Machine learning algorithm predicts skip metastasis in papillary thyroid cancer in retrospective cohort
- Meta-analysis finds Qi-deficiency constitution most prevalent in nasopharyngeal carcinoma health states
- Phase 3 trial compares pembrolizumab with or without lenvatinib in PD-L1+ recurrent/metastatic HNSCC
- PD-1 inhibitors + chemo improve OS, PFS, ORR in first-line advanced ESCC; benefit limited in PD-L1 CPS <1
- Meta-analysis: PD-1/PD-L1 inhibitors show 45% ORR, 16.27-month median OS in recurrent/metastatic NPC
- Photobiomodulation reduces severe oral mucositis (RR 0.46) and pain (RR 0.35) in head and neck cancer patients