N/A Completed N=18 Basic Science

A Novel Positron Emission Tomography (PET) Approach to Measuring Myocardial Metabolism

Type 2 Diabetes Mellitus

Source: ClinicalTrials.gov NCT02563834 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Aug 2016

Primary outcomePrimary: Myocardial Fatty Acid Uptake Rate — 18.492; 2.123; 36.005; 7.8 umol/min/100g

Summary

Studies of myocardial fuel selection using a novel palmitate-based PET probe

Outcome Measures

Outcome	Result	p-value
PRIMARY Myocardial Fatty Acid Uptake Rate	18.492; 2.123; 36.005; 7.8	—
SECONDARY Myocardial Oxidation Rate	15.006; 19.847; 17.381; 22.940	—
SECONDARY Myocardial Perfusion Rate	39.3; 46.5; 44.2; 49.4	—

Eligibility Criteria

Inclusion Criteria

Lean:
BMI 25 kg/m2
previously diagnosed type 2 diabetes mellitus
on oral and/or injected insulin treatment.

Exclusion Criteria

Lean:

*Use of any chronic medications

Type 2 diabetes mellitus
known microvascular disease
known coronary or other macro vascular disease
use of PPARgamma class antidiabetic agents within 6 months

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02563834). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.