N/A N=120 Randomized Quadruple-blind Treatment

Initiation of Hydrocortisone for the Treatment of Septic Shock

Septic Shock

Bottom Line

View on ClinicalTrials.gov: NCT02580240 ↗

Enrolled (actual)

120

Serious AEs

0.9%

Results posted

Aug 2017

Primary outcome: Primary: 28-day Mortality — 19; 23 Participants

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Hydrocortisone (Drug); saline (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Northern Jiangsu People's Hospital
Primary completion: Sep 2016

Outcome Measures

Outcome	Result	p-value
PRIMARY 28-day Mortality	19; 23	—
SECONDARY All Cause Mortality	19; 23	—

Summary

The purpose of this study : 1）to determine whether hydrocortisone is effective in the treatment of septic shock and 2) to identify the role of timing of low dose hydrocortisone administration in septic shock patients.

Eligibility Criteria

Inclusion Criteria

age 18 years old or older;
onset of septic shock within 6 h

Exclusion Criteria

Systemic corticosteroid therapy within the last 3 months before septic shock;
high-dose steroid therapy;
immunosuppression;
refusal of the attending staff or patient family.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02580240). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.