N/A
Completed N=126
Ethyl Chloride Vapocoolant as Anesthesia for Arterial Punctures
Source: ClinicalTrials.gov NCT02587143 ↗Enrolled (actual)
126
Serious AEs
0.0%
Results posted
Jan 2020
Primary outcomePrimary: Pain Level on the Visual Analog Scale (NRS-11) — 2; 2 scores on scale
Summary
Ethyl chloride vapocoolant sprays provide transient skin anesthesia within seconds of application. The current investigation aim is to compare the effect of ethyl chloride based vapocoolant spray to placebo in reducing pain associated with arterial puncture for gasometry determinations.
The investigators will conduce a double-blind randomized placebo-controlled trial at Emergency Department.
We will enroll patients who come to Emergency Department who need an arterial gasometry determination. Patients will be randomized to intervention-group (ethyl chloride vapocoolant sprays will be usad before arterial puncture) or to placebo-group (alcohol spray as placebo will be used before arterial puncture.) and after the puncture they will rate their pain using a 10 points visual analogue scale.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Pain Level on the Visual Analog Scale (NRS-11) |
2; 2 | — |
Eligibility Criteria
Inclusion Criteria
- age: 18-85 years old.
- arterial gasometry determination needed
- III, IV or V level classification on Manchester triage.
Exclusion criteria
- refusal to participate,
- inability to provide informed consent (non-Spanish speaking, dementia or altered mental state),
- skin disease associated with cold intolerance (Raynaud's phenomenon),
- known allergy to spray contents,
- Glasgow Coma Scale <15,
- pregnancy,
- under effects of alcohol or drugs,
- Allen test +.
Data sourced from ClinicalTrials.gov (NCT02587143). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.