N/A Completed N=22 Supportive Care

Cytosponge and Dietary Therapy in EoE

Eosinophilic Esophagitis

Source: ClinicalTrials.gov NCT02599558 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Dec 2022

Primary outcomePrimary: Histological Remission by Sponge Cytology — 13 Participants

Summary

This study is being done to see if the investigators can use only the cytosponge ( A 10 minute, in office procedure that does not require sedation) to replace the 6-10 endoscopies routinely perform during dietary restriction and food reintroduction in EoE?

Outcome Measures

Outcome	Result	p-value
PRIMARY Histological Remission by Sponge Cytology	13	—
SECONDARY Eosinophilic Esophagitis Activity Index Patient Reported Outcomes (EEsAI PRO) Score	16.5	—

Eligibility Criteria

Inclusion Criteria

Diagnosed with Eosinophilic Esophagitis > than 15 Eos phf and failed to respond to the PPI therapy
Going through the six food elimination diet or have just completed elimination the six foods: fish, nuts, eggs, soy, wheat, and milk

Exclusion Criteria

Clinical evidence of infectious process potentially contributing to dysphagia ( candidiasis, CMV, herpes)
Other cause of dysphagia identified at endoscopy (e.g. reflux esophagitis, stricture, web, ring, achalasia, esophageal neoplasm)
Esophageal minimal diameter < 13 mm on structured barium esophagram

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02599558). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.