N/A
N=75
Vibratory Stimuli, A Novel Rehabilitation Method for Preventing Post - Traumatic Knee Osteoarthritis
Knee Osteoarthritis
Bottom Line
View on ClinicalTrials.gov: NCT02605876 ↗Enrolled (actual)
75
Serious AEs
0.0%
Results posted
Nov 2019
Primary outcome: Primary: Linear Ground Reaction Force Loading Rate — 0.276; -0.146; -0.135 multiples of body weight per second
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Whole body vibration (Device); Local muscle vibration (Device)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of North Carolina, Chapel Hill
- Primary completion
- Dec 2018
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Linear Ground Reaction Force Loading Rate |
0.276; -0.146; -0.135 | — |
| PRIMARY Quadriceps Strength |
0.05; -0.13; -0.09 | — |
| PRIMARY Knee Proprioception |
-0.71; -0.61; -0.08 | — |
| PRIMARY Instantaneous Ground Reaction Force Loading Rate |
-0.333; -3.552; 0.473 | — |
| SECONDARY Peak Internal Knee Extension Moment |
0.271; 0.014; -0.17 | — |
| SECONDARY Peak Internal Knee Valgus Moment |
-0.450; -0.436; -0.304 | — |
Summary
This study will evaluate the acute effects of vibration (whole body vibration and local muscle vibration) on quadriceps function, knee joint proprioception, and gait biomechanics linked to osteoarthritis development in individuals with anterior cruciate ligament reconstruction. Subjects will be randomly assigned to control (no vibration), whole body vibration, and local muscle vibration groups, and the aforementioned characteristics will be assessed prior to and following the respective interventions.
Eligibility Criteria
Inclusion Criteria
- age 18-35 years
- undergone unilateral ACLR within 5 years prior to participation
- at least 6 months post-ACLR
- Knee Injury and Osteoarthritis Outcome Score (KOOS) self-report survey Pain subscale score > 53.1 and Symptom subscale score > 44.9
- cleared by a physician for return to physical activity, and currently participating in at least 20 minutes of physical activity 3x per week.
Exclusion Criteria
- central activation ratio (CAR) > 95%
- history of ACL graft rupture or revision surgery, neurological disorder, or injury to either leg within 6 months prior to participation (other than the initial ACLR)
Data sourced from ClinicalTrials.gov (NCT02605876). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.