Phase 1
Completed N=57
The Capillary Index Score Trial
Stroke · Brain Ischemia
Source: ClinicalTrials.gov NCT02618031 ↗
Enrolled (actual)
57
Serious AEs
1.8%
Results posted
Feb 2020
Primary outcomePrimary: Modified Rankin Score (mRS) Between Favorable CIS Group Versus Poor CIS Group. — 22; 1; 23; 10 Participants
Summary
This study seeks to investigate the capillary index score (CIS) to further improve patient selection of endovascular treatment (EVT) in acute ischemic stroke (AIS).
The hypothesis or idea being tested:
Patients with favorable CIS who are successfully revascularized with EVT can have successful outcomes with an extended time window for treatment.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Modified Rankin Score (mRS) Between Favorable CIS Group Versus Poor CIS Group. |
22; 1; 23; 10 | — |
| SECONDARY Complication Rate Between Favorable CIS Group Versus Poor CIS Group |
1; 4; 44; 6 | — |
| SECONDARY Modified Rankin Score (mRS) Between Favorable CIS With Good Revascularization Versus Poor CIS With Good Revascularization. |
19; 1; 3; 0; 17; 7 | — |
Eligibility Criteria
Inclusion Criteria
- Anterior circulation acute ischemic stroke due to blockage of the intracranial internal carotid artery or middle cerebral artery (M1)
- Within 24 hours of onset of symptoms
- NIHSS Score is 8 or greater
Exclusion Criteria
- Contra-indication for IAT found on initial CT
- Intracranial hemorrhage
- Stroke mimics (tumor, herpetic encephalitis, etc.)
- More than 1/3 hypodensity on non-enhanced head CT prior to intervention
- ASPECT Score less than 6
- Pre-existing disability defined as modified Rankin Scale (mRS) score more than 2
- Pregnant women
Data sourced from ClinicalTrials.gov (NCT02618031). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.