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Early Phase 1 N=34 Randomized Single-blind Treatment

Characteristics of Balance Control to Unexpected Loss of Balance During Standing and Walking in Post-stroke Individuals

Stroke

Enrolled (actual)
34
Serious AEs
0.0%
Results posted
Sep 2019
Primary outcome: Primary: Change in Compensatory Step Execution Time — -119.7; -4.2 msec

Study Design & Population

Study type
Interventional
Phase
Early Phase 1
Interventions
Stroke Subjects Perturbation-Based Balance Training (Device); Stroke Subjects Weight Shifting and Gait training (Device)
Age
Adult, Older Adult · 25+ yrs
Sex
All
Sponsor
Nachum Soroker, MD
Primary completion
Mar 2019

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Compensatory Step Execution Time
-119.7; -4.2
PRIMARY
Change in Compensatory Step Velocity
0.05; -0.05
SECONDARY
Change in Berg Balance Scale Score
5.7; 5.8
SECONDARY
Change in Fall Threshold
1.93; 1.12
SECONDARY
Change in Activities-specific Balance Confidence (ABC) Scale
17.9; 4.1

Summary

aim: To examine the effect of a perturbation-based balance training on balance reaction characteristics in post stroke individuals.

Eligibility Criteria

Inclusion Criteria

For measurements taken while standing, post stroke subjects will meet the criteria of being able to stand independently or with supervision for at least 2 minutes.

For measurements taken while walking, post stroke subjects will meet the criteria of being able to walk for at least 10 meter with supervision/independently without walking aids.

  • 3 weeks-6 months post stroke (hemorrhage/infarct)
  • First stroke
  • Age 25-75 years
  • Able to understand research instructions
  • Stable clinical/metabolic state

Exclusion Criteria

  • - A history of neurological diseases amongst peripheral neuropathy
  • Significant skeletal system diseases, such as severe osteoporosis
  • Uncontrolled atrial fibrillation
  • Unstable ischemic heart disease
  • Significant visual deficiency
  • Dizziness
  • Pregnancy
  • Body weight above 135 kg
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02619175). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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