N/A N=33 Randomized Diagnostic

Analysis of the Eye in Patients With Primary Open-Angle Glaucoma and a Visual Field Defect in One Eye

Glaucoma

Bottom Line

View on ClinicalTrials.gov: NCT02622191 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Feb 2019

Primary outcome: Primary: Lamina Cribrosa (Boundaries of the Retinal Layers) Measurements — 264.3; 273.3; 276.2 micro-ohms

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Spectral domain Optical Coherence Tomography (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Wills Eye
Primary completion: Feb 2013

Outcome Measures

Outcome	Result	p-value
PRIMARY Lamina Cribrosa (Boundaries of the Retinal Layers) Measurements	264.3; 273.3; 276.2	—

Summary

The study aims to further understand glaucoma pathogenesis and progression by utilizing enhanced depth imaging optical coherence tomography to visualize and measure lamina cribrosa in vivo and segmentation technology to accurately delineate and measure boundaries of the retinal layers. Investigators will elaborate further on key concepts of lamina cribrosa thickness and trans-synaptic degeneration.

Eligibility Criteria

Inclusion Criteria

Best-corrected visual acuity of 20/40 or better
No media opacities
Spherical equivalent refractive errors in a range of -6 to +6 diopters
Cylinder correction within 3.0 diopters.

Exclusion Criteria

Age +2
Corneal diseases
Contact lens use
History of posterior segment intraocular surgery
Systemic or ocular diseases that can cause visual field loss.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02622191). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.