N/A
Completed N=76
180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for Glaucoma
Open-angle glaucoma · Hypertension · Glaucoma, Open Angle, Pseudo-exfoliative · Pigment Dispersion Syndrome
Source: ClinicalTrials.gov NCT02628223 ↗
Enrolled (actual)
76
Serious AEs
0.0%
Results posted
Nov 2020
Primary outcomePrimary: Intraocular Pressure (IOP) Measured by Tonometry in Millimeters of Mercury at Three Months of Follow-up — 20.7; 19.1 mm Hg
Summary
Selective laser trabeculoplasty (SLT) is a well-recognized way to lower eye pressure in treatment of glaucoma. This treatment is performed for 180 degrees or 360 degrees, and studies at academic centers have shown mixed results when comparing the success rates of 180 degrees or 360 degrees. Both protocols are now typically done by comprehensive ophthalmologists. However, there is no data that compares success rates of 180 degrees and 360 degrees in the community setting.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Intraocular Pressure (IOP) Measured by Tonometry in Millimeters of Mercury at Three Months of Follow-up |
20.7; 19.1 | — |
| SECONDARY Intraocular Pressure (IOP) Measured by Tonometry in Millimeters of Mercury at 1 Year of Follow-up |
18.7; 19.0 | — |
| SECONDARY Intraocular Pressure (IOP) Measured by Tonometry in Millimeters of Mercury at Time at Which Additional Glaucoma Therapy is Required |
24.7; 23.7 | — |
| SECONDARY Intraocular Pressure (IOP) Measured by Tonometry in Millimeters of Mercury at Last Follow-up |
18.2; 18.3 | — |
Eligibility Criteria
Inclusion Criteria
- patients who have been diagnosed with open-angle glaucoma including ocular hypertension, pseudoexfoliation and pigment dispersion syndrome
- greater than 18 years of age
- initial intraocular pressure (IOP) of ≥ 21 mmHg
Exclusion Criteria
- prior medical or laser therapy to lower IOP
- previous incisional glaucoma surgery before the study period
Data sourced from ClinicalTrials.gov (NCT02628223). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.