Netarsudil plus latanoprost cuts diurnal IOP 2.36 mmHg vs latanoprost alone in Japanese glaucoma
Adding netarsudil to latanoprost lowers eye pressure faster in Japanese patients with glaucoma
This Phase III randomized controlled trial in 246 Japanese participants with primary open-angle glaucoma or ocular hypertension found that n…
Japanese patients with glaucoma saw lower eye pressure when adding netarsudil to their current latanoprost drops compared to a placebo plus …
Baseline disc hemorrhage strongly predicts progression in primary open-angle and normal tension glaucoma
Disc hemorrhage predicts faster vision loss in glaucoma patients
This systematic review and meta-analysis of 22 papers found that baseline disc hemorrhage is associated with progression in primary open-ang…
A blood spot on the optic nerve signals a higher risk of disease progression in patients with primary open-angle or normal tension glaucoma.
Netarsudil shows lower IOP reduction but better conjunctival hyperemia profile versus prostaglandin analogues
New data shows netarsudil offers a safer option for some glaucoma patients
A Bayesian network meta-analysis found netarsudil ranked lower for IOP reduction but had a more favorable conjunctival hyperemia profile com…
A fresh look at glaucoma drugs shows one option causes less redness while still helping lower eye pressure effectively.
Meta-analysis of tafluprost-timolol fixed-dose combination for open-angle glaucoma and ocular hypertension
Tafluprost-timolol drops lower eye pressure than switching to single drugs
This meta-analysis evaluated the tafluprost-timolol fixed-dose combination versus a monotherapy switch group in patients with open-angle gla…
A meta-analysis of 2066 patients found that fixed-dose tafluprost-timolol lowered eye pressure more than switching to monotherapy, with mini…
Bleb Wall Thickness Not Associated With Secondary Interventions After Preserflo MicroShunt Implantation
Early bleb scans do not predict future surgery needs in glaucoma
This observational cohort study evaluated 23 open-angle glaucoma patients undergoing Preserflo MicroShunt implantation.
Early bleb measurements after glaucoma surgery do not predict which patients will need additional treatment procedures later.
Glaucoma surgery in children with primary congenital or juvenile open-angle glaucoma shows persistent vessel narrowing and cup reversal
Study tracks eye blood vessel changes after glaucoma surgery in children
This prospective, comparative cohort study evaluated 24 glaucomatous eyes and 24 age-matched normal control eyes.
Glaucoma surgery in children lowers eye pressure but leaves tiny blood vessels around the optic nerve abnormally narrow even after the opera…
Meta-analysis finds contralateral IOP reduction after unilateral selective laser trabeculoplasty
Unilateral SLT treatment linked to lower pressure in the other eye
A systematic review and meta-analysis of 9 studies (478 eyes) in POAG and OHT patients found unilateral SLT was associated with a mean contr…
Treating one eye with laser therapy lowers pressure in the other eye by an average of 1.85 mmHg without reported safety concerns.
Research across Glaucoma
Related studies from across the Glaucoma family.
Metformin use linked to modest glaucoma risk reduction in diabetic patients
Metformin use linked to lower glaucoma risk in people with diabetes
A large meta-analysis of diabetic patients found metformin use associated with a modest reduction in glaucoma incidence, though evidence cer…
A massive review of over 1.2 million patients suggests metformin might lower the chance of developing glaucoma compared to other diabetes dr…
Integrated care combining antiangiogenic bridging and ischemia-directed therapies supports long-term success in neovascular glaucoma management
Integrated care offers long-term success for neovascular glaucoma
This narrative review addresses neovascular glaucoma management in patients with retinal ischemia. The authors argue that long-term success …
A review suggests combining antiangiogenic bridging with ischemia management and surgery may help patients with neovascular glaucoma achieve…
Review of glaucoma management without reported intervention details or outcomes
Review finds no clear best treatment for glaucoma
This narrative review addresses glaucoma management but does not report specific interventions, comparators, or outcomes. The authors provid…
A review of glaucoma treatments found no single approach is clearly best. What this means for patients.
Motivational Interviewing Workshop Improves Communication Skills in Ophthalmology Residents
Motivational Interviewing Workshop Boosts Glaucoma Counseling Skills
This pilot RCT with 20 ophthalmology residents found that a 1-hour Motivational Interviewing workshop improved standardized patient encounte…
A simple one-hour class helps doctors talk to glaucoma patients in ways that actually change behavior and improve medication use.
Perioperative taVNS Reduces Pain and Insomnia After Glaucoma Surgery
Vagus nerve stimulation lowers pain after glaucoma surgery
This randomized trial of 94 patients undergoing glaucoma surgery found that perioperative transcutaneous auricular vagus nerve stimulation (…
A trial found that vagus nerve stimulation reduced pain and improved sleep for patients having glaucoma surgery under general anesthesia.
Retrospective review links higher TAPE score to better SLT outcomes in glaucoma
New laser settings help lower eye pressure for years without extra drops
This retrospective review of 62 eyes undergoing lower-energy SLT found that higher TAPE scores were associated with lower IOP at 2 months an…
A new way to tune laser energy for glaucoma could keep pressure low for years while avoiding the need for daily eye drops.
Micropulse transscleral cyclophotocoagulation showed less pain and inflammation than continuous-wave in refractory glaucoma patients
New laser option for hard-to-treat glaucoma cuts pain and swelling
This prospective, randomized, single-blind study enrolled 52 patients with refractory glaucoma.
A gentler laser lowers eye pressure as well as older methods but causes less pain and swelling.
Review of portable visual field devices shows higher patient preference over table-mounted analyzers in rural glaucoma care
Portable eye tests beat old machines for rural patients
This mixed methods review analyzed patient preferences among 271 respondents at three Alabama Federally Qualified Health Centers.
Rural patients with glaucoma preferred portable virtual reality eye tests over traditional machines, reporting higher satisfaction and comfo…
Polygenic risk score enrichment reduces sample size needs for coronary artery disease and inflammatory bowel disease trials
Smarter trial designs could cut study sizes by 60% for heart disease
This in silico observational cohort study used UK Biobank data to model trial designs enriched for polygenic risk.
Using genetic risk scores to pick high-risk volunteers could shrink trial sizes by 60% for heart disease and 78% for IBD, speeding up resear…
Preclinical study tests AI pipeline for glaucoma detection using Harvard dataset
New AI System Catches Glaucoma Cases That Other Tools Miss
This preclinical study evaluated a two-tier AI diagnostic pipeline for glaucoma using the Harvard Glaucoma Detection and Progression dataset…
This approach may help doctors spot glaucoma earlier by using AI to double-check its own uncertain findings.
GATT reduces IOP in normal-tension glaucoma patients over 24 months
GATT Surgery Lowers Eye Pressure for Years
This single-center retrospective case series evaluated gonioscopy-assisted transluminal trabeculotomy (GATT) in 9 patients with normal-tensi…
GATT surgery lowered eye pressure by an average of 4 mmHg for two years in patients with normal-tension glaucoma, offering a long-term alter…
Rare LOXL1 variants associated with exfoliation syndrome and secondary glaucoma risk in US cohorts
Rare Gene Changes Might Protect Against Glaucoma
This cohort study analyzed exome array and sequence data from 1118 XFS/XFG cases and 3661 controls in the Mass Eye and Ear cohort, plus 284 …
Rare genetic changes in a specific eye gene may protect against glaucoma, offering hope for those with a family history of vision loss.