Unadjusted hazard ratio of 2.14 for mortality in primary open-angle glaucoma patients
Understanding the link between glaucoma and overall health risks for patients
This meta-analysis evaluates the mortality risk associated with various types of glaucoma, including POAG, PACG, and congenital glaucoma. Th…
A large review shows that people with certain types of glaucoma may face higher health risks, highlighting the need for full-body care.
Phacoemulsification addition to ab-interno canaloplasty does not significantly improve intraocular pressure or medication reduction
Adding cataract surgery to canaloplasty does not change glaucoma results
This meta-analysis of 663 eyes evaluated the impact of combining phacoemulsification with ab-interno canaloplasty (ABiC) for open-angle glau…
Combining cataract surgery with a specific eye procedure called canaloplasty does not provide extra benefits for lowering pressure in glauco…
C-reactive protein levels significantly higher in normal tension glaucoma patients
Inflammation marker linked to one type of glaucoma
This meta-analysis of 766 patients found significantly higher CRP levels in normal tension glaucoma (NTG) compared to controls, but no signi…
People with normal tension glaucoma had higher CRP levels, a sign of inflammation, than those without glaucoma. The finding may help identif…
XEN-only surgery achieves lower postoperative IOP than trabeculectomy but has higher bleb needling rates
New analysis compares surgical options for open angle glaucoma
This systematic review and meta-analysis of 56 studies compared XEN-only, Phaco-XEN, and trabeculectomy for open-angle glaucoma. Findings in…
Two different surgery types for glaucoma both lower eye pressure, but one method may lead to fewer complications during follow-up care.
Netarsudil plus latanoprost cuts diurnal IOP 2.36 mmHg vs latanoprost alone in Japanese glaucoma
Adding netarsudil to latanoprost lowers eye pressure faster in Japanese patients with glaucoma
This Phase III randomized controlled trial in 246 Japanese participants with primary open-angle glaucoma or ocular hypertension found that n…
Japanese patients with glaucoma saw lower eye pressure when adding netarsudil to their current latanoprost drops compared to a placebo plus …
Baseline disc hemorrhage strongly predicts progression in primary open-angle and normal tension glaucoma
Disc hemorrhage predicts faster vision loss in glaucoma patients
This systematic review and meta-analysis of 22 papers found that baseline disc hemorrhage is associated with progression in primary open-ang…
A blood spot on the optic nerve signals a higher risk of disease progression in patients with primary open-angle or normal tension glaucoma.
Netarsudil shows lower IOP reduction but better conjunctival hyperemia profile versus prostaglandin analogues
New data shows netarsudil offers a safer option for some glaucoma patients
A Bayesian network meta-analysis found netarsudil ranked lower for IOP reduction but had a more favorable conjunctival hyperemia profile com…
A fresh look at glaucoma drugs shows one option causes less redness while still helping lower eye pressure effectively.
Meta-analysis of tafluprost-timolol fixed-dose combination for open-angle glaucoma and ocular hypertension
Tafluprost-timolol drops lower eye pressure than switching to single drugs
This meta-analysis evaluated the tafluprost-timolol fixed-dose combination versus a monotherapy switch group in patients with open-angle gla…
A meta-analysis of 2066 patients found that fixed-dose tafluprost-timolol lowered eye pressure more than switching to monotherapy, with mini…
Bleb Wall Thickness Not Associated With Secondary Interventions After Preserflo MicroShunt Implantation
Early bleb scans do not predict future surgery needs in glaucoma
This observational cohort study evaluated 23 open-angle glaucoma patients undergoing Preserflo MicroShunt implantation.
Early bleb measurements after glaucoma surgery do not predict which patients will need additional treatment procedures later.
Glaucoma surgery in children with primary congenital or juvenile open-angle glaucoma shows persistent vessel narrowing and cup reversal
Study tracks eye blood vessel changes after glaucoma surgery in children
This prospective, comparative cohort study evaluated 24 glaucomatous eyes and 24 age-matched normal control eyes.
Glaucoma surgery in children lowers eye pressure but leaves tiny blood vessels around the optic nerve abnormally narrow even after the opera…
Meta-analysis finds contralateral IOP reduction after unilateral selective laser trabeculoplasty
Unilateral SLT treatment linked to lower pressure in the other eye
A systematic review and meta-analysis of 9 studies (478 eyes) in POAG and OHT patients found unilateral SLT was associated with a mean contr…
Treating one eye with laser therapy lowers pressure in the other eye by an average of 1.85 mmHg without reported safety concerns.
Research across Glaucoma
Related studies from across the Glaucoma family.
Ocular morbidity prevalence of 43.1% among incarcerated populations in sub-Saharan Africa
Factors Linked to Eye Conditions in Sub-Saharan African Prisons
This meta-analysis of 3,361 individuals in sub-Saharan African prisons identifies a 43.1% prevalence of ocular morbidity. Key associated fac…
A study of over 3,000 people in African prisons found that age, past injuries, and length of stay are linked to common eye conditions.
Rheumatic diseases linked to 66% higher glaucoma risk in pooled analysis
Rheumatic Diseases Linked to Higher Risk of Glaucoma
This meta-analysis examined glaucoma incidence and risk in individuals with rheumatic diseases versus the general population. Pooled data sh…
People with rheumatic diseases may face a 66% higher risk of developing glaucoma compared to the general population.
Dysregulation of intraocular immune pathways plays a central role in progressive retinal ganglion cell death
Immune Pathways Play Central Role in Glaucoma Progression
This systematic review examines the role of intraocular immune pathways, including microglia, astrocytes, and T cells, in glaucoma progressi…
New research highlights how immune system issues inside the eye may contribute to the death of nerve cells in glaucoma patients.
Transconjunctival bleb needling with mitomycin C reduces intraocular pressure in pediatric congenital glaucoma
New surgical technique helps manage severe glaucoma in children
This case report describes a 9-year-old patient with refractory primary congenital glaucoma. Transconjunctival bleb needling with mitomycin …
A minimally invasive procedure helped lower high eye pressure in a child with severe glaucoma and a complex surgical history.
Intraluminal stent removal from Paul glaucoma implants significantly reduces intraocular pressure in glaucoma patients
Stent Removal Reduces Eye Pressure in Glaucoma Patients
This meta-analysis of 5 observational studies indicates that removing the intraluminal stent from a Paul glaucoma implant (PGI) significantl…
Removing a specific internal stent from a glaucoma implant can significantly lower eye pressure, especially for patients with high initial p…
Medicinal mushroom-derived compounds show potential for managing oxidative stress and inflammation in ocular conditions
Medicinal mushrooms show promise for several common eye conditions
This narrative review synthesizes evidence regarding medicinal mushroom-derived bioactive compounds, including polysaccharides and triterpen…
Medicinal mushrooms contain compounds that may protect the eyes from inflammation and damage, though more clinical trials are needed to conf…
Oxidative stress and reactive oxygen species mediate retinal ganglion cell death and optic nerve damage
Oxidative stress and nerve damage drive glaucoma progression
This narrative review explores the role of oxidative stress and reactive oxygen species (ROS) as key mediators of retinal ganglion cell deat…
New research identifies how oxidative stress and reactive oxygen species damage the optic nerve in people with glaucoma.
Postoperative glaucoma occurs in 25.6% of eyes following Boston Type 1 Keratoprosthesis implantation
Meta-analysis tracks glaucoma risks after Boston Type 1 Keratoprosthesis
This meta-analysis of 1,482 eyes evaluates glaucoma outcomes following Boston Type 1 Keratoprosthesis (KPro) implantation. The study reports…
A meta-analysis of 1,482 eyes shows that about 25.6% of patients experience some form of glaucoma after a Boston Type 1 Keratoprosthesis pro…
Preservative Free Bimatoprost 0.01% Shows Non Inferiority to Higher Concentration Formulations
Preservative-free bimatoprost shows similar results for glaucoma eye pressure
Preservative-free bimatoprost 0.01% provides comparable intraocular pressure reduction to higher concentrations with improved local tolerabi…
A new look at eye drops shows that preservative-free bimatoprost lowers eye pressure as well as stronger versions with fewer side effects.
Photobiomodulation protocol aims to consolidate preclinical evidence for ophthalmic diseases
Planning to Review Light Therapy for Common Eye Diseases and Injuries
This is a protocol for a systematic review and meta-analysis, not a completed study. It outlines plans to evaluate photobiomodulation (PBM) …
Experts are planning a large review to see if light therapy can help treat common eye problems like glaucoma and vision loss.
Portable visual-field testing devices show 86% sensitivity and 88% specificity for glaucoma diagnosis
Portable devices show promise for diagnosing glaucoma more quickly
This meta-analysis of 2,254 participants with glaucoma and controls evaluated the diagnostic accuracy of portable visual-field testing devic…
New research suggests portable vision tests can accurately detect glaucoma while significantly cutting down the time patients spend in testi…
Glucocorticoid signaling and stress-related neuroendocrine dysregulation influence intraocular pressure and inflammatory pathways in ocular diseases
Stress and hormones may play a role in eye health
This narrative literature overview of 35 studies synthesizes the role of glucocorticoid signaling and stress-related neuroendocrine dysregul…
New research suggests that stress-related hormone changes could influence conditions like glaucoma and other serious eye diseases.