Unadjusted hazard ratio of 2.14 for mortality in primary open-angle glaucoma patients
Understanding the link between glaucoma and overall health risks for patients
This meta-analysis evaluates the mortality risk associated with various types of glaucoma, including POAG, PACG, and congenital glaucoma. Th…
A large review shows that people with certain types of glaucoma may face higher health risks, highlighting the need for full-body care.
Phacoemulsification addition to ab-interno canaloplasty does not significantly improve intraocular pressure or medication reduction
Adding cataract surgery to canaloplasty does not change glaucoma results
This meta-analysis of 663 eyes evaluated the impact of combining phacoemulsification with ab-interno canaloplasty (ABiC) for open-angle glau…
Combining cataract surgery with a specific eye procedure called canaloplasty does not provide extra benefits for lowering pressure in glauco…
C-reactive protein levels significantly higher in normal tension glaucoma patients
Inflammation marker linked to one type of glaucoma
This meta-analysis of 766 patients found significantly higher CRP levels in normal tension glaucoma (NTG) compared to controls, but no signi…
People with normal tension glaucoma had higher CRP levels, a sign of inflammation, than those without glaucoma. The finding may help identif…
XEN-only surgery achieves lower postoperative IOP than trabeculectomy but has higher bleb needling rates
New analysis compares surgical options for open angle glaucoma
This systematic review and meta-analysis of 56 studies compared XEN-only, Phaco-XEN, and trabeculectomy for open-angle glaucoma. Findings in…
Two different surgery types for glaucoma both lower eye pressure, but one method may lead to fewer complications during follow-up care.
Netarsudil plus latanoprost cuts diurnal IOP 2.36 mmHg vs latanoprost alone in Japanese glaucoma
Adding netarsudil to latanoprost lowers eye pressure faster in Japanese patients with glaucoma
This Phase III randomized controlled trial in 246 Japanese participants with primary open-angle glaucoma or ocular hypertension found that n…
Japanese patients with glaucoma saw lower eye pressure when adding netarsudil to their current latanoprost drops compared to a placebo plus …
Baseline disc hemorrhage strongly predicts progression in primary open-angle and normal tension glaucoma
Disc hemorrhage predicts faster vision loss in glaucoma patients
This systematic review and meta-analysis of 22 papers found that baseline disc hemorrhage is associated with progression in primary open-ang…
A blood spot on the optic nerve signals a higher risk of disease progression in patients with primary open-angle or normal tension glaucoma.
Netarsudil shows lower IOP reduction but better conjunctival hyperemia profile versus prostaglandin analogues
New data shows netarsudil offers a safer option for some glaucoma patients
A Bayesian network meta-analysis found netarsudil ranked lower for IOP reduction but had a more favorable conjunctival hyperemia profile com…
A fresh look at glaucoma drugs shows one option causes less redness while still helping lower eye pressure effectively.
Meta-analysis of tafluprost-timolol fixed-dose combination for open-angle glaucoma and ocular hypertension
Tafluprost-timolol drops lower eye pressure than switching to single drugs
This meta-analysis evaluated the tafluprost-timolol fixed-dose combination versus a monotherapy switch group in patients with open-angle gla…
A meta-analysis of 2066 patients found that fixed-dose tafluprost-timolol lowered eye pressure more than switching to monotherapy, with mini…
Bleb Wall Thickness Not Associated With Secondary Interventions After Preserflo MicroShunt Implantation
Early bleb scans do not predict future surgery needs in glaucoma
This observational cohort study evaluated 23 open-angle glaucoma patients undergoing Preserflo MicroShunt implantation.
Early bleb measurements after glaucoma surgery do not predict which patients will need additional treatment procedures later.
Glaucoma surgery in children with primary congenital or juvenile open-angle glaucoma shows persistent vessel narrowing and cup reversal
Study tracks eye blood vessel changes after glaucoma surgery in children
This prospective, comparative cohort study evaluated 24 glaucomatous eyes and 24 age-matched normal control eyes.
Glaucoma surgery in children lowers eye pressure but leaves tiny blood vessels around the optic nerve abnormally narrow even after the opera…
Meta-analysis finds contralateral IOP reduction after unilateral selective laser trabeculoplasty
Unilateral SLT treatment linked to lower pressure in the other eye
A systematic review and meta-analysis of 9 studies (478 eyes) in POAG and OHT patients found unilateral SLT was associated with a mean contr…
Treating one eye with laser therapy lowers pressure in the other eye by an average of 1.85 mmHg without reported safety concerns.
Research across Glaucoma
Related studies from across the Glaucoma family.
Oxidative stress and reactive oxygen species mediate retinal ganglion cell death and optic nerve damage
Oxidative stress and nerve damage drive glaucoma progression
This narrative review explores the role of oxidative stress and reactive oxygen species (ROS) as key mediators of retinal ganglion cell deat…
New research identifies how oxidative stress and reactive oxygen species damage the optic nerve in people with glaucoma.
Postoperative glaucoma occurs in 25.6% of eyes following Boston Type 1 Keratoprosthesis implantation
Meta-analysis tracks glaucoma risks after Boston Type 1 Keratoprosthesis
This meta-analysis of 1,482 eyes evaluates glaucoma outcomes following Boston Type 1 Keratoprosthesis (KPro) implantation. The study reports…
A meta-analysis of 1,482 eyes shows that about 25.6% of patients experience some form of glaucoma after a Boston Type 1 Keratoprosthesis pro…
Preservative Free Bimatoprost 0.01% Shows Non Inferiority to Higher Concentration Formulations
Preservative-free bimatoprost shows similar results for glaucoma eye pressure
Preservative-free bimatoprost 0.01% provides comparable intraocular pressure reduction to higher concentrations with improved local tolerabi…
A new look at eye drops shows that preservative-free bimatoprost lowers eye pressure as well as stronger versions with fewer side effects.
Photobiomodulation protocol aims to consolidate preclinical evidence for ophthalmic diseases
Planning to Review Light Therapy for Common Eye Diseases and Injuries
This is a protocol for a systematic review and meta-analysis, not a completed study. It outlines plans to evaluate photobiomodulation (PBM) …
Experts are planning a large review to see if light therapy can help treat common eye problems like glaucoma and vision loss.
Portable visual-field testing devices show 86% sensitivity and 88% specificity for glaucoma diagnosis
Portable devices show promise for diagnosing glaucoma more quickly
This meta-analysis of 2,254 participants with glaucoma and controls evaluated the diagnostic accuracy of portable visual-field testing devic…
New research suggests portable vision tests can accurately detect glaucoma while significantly cutting down the time patients spend in testi…
Glucocorticoid signaling and stress-related neuroendocrine dysregulation influence intraocular pressure and inflammatory pathways in ocular diseases
Stress and hormones may play a role in eye health
This narrative literature overview of 35 studies synthesizes the role of glucocorticoid signaling and stress-related neuroendocrine dysregul…
New research suggests that stress-related hormone changes could influence conditions like glaucoma and other serious eye diseases.
Glaucoma prevalence in Africa varies widely with diagnostic criteria; standardized ISGEO definitions narrow estimates
Standardized rules help track how common glaucoma is in Africa
This systematic review of 9 population-based studies in Africa found that glaucoma prevalence estimates range from 4.3% to 5.3% when using f…
Using consistent diagnostic rules for glaucoma helps doctors get a clearer picture of how many people are affected across different regions.
Surgical intervention improves refractive error and visual acuity in short eyes
Surgery Improves Vision Outcomes for Patients with Short Eyes
This systematic review and meta-analysis of 1,110 eyes indicates that surgical procedures significantly improve visual acuity and refractive…
New analysis shows surgical procedures can improve vision and eye measurements for patients with specific conditions like nanophthalmos and …
Dynamic gratings serve as tools for diagnosis and treatment evaluation in neuro-ophthalmic conditions
Dynamic gratings help doctors understand and treat eye conditions
This narrative review explores the use of dynamic gratings, such as phase-alternating oscillation and rapid serial visual presentation, to e…
Moving patterns on a screen, called dynamic gratings, offer new ways to study and treat vision issues like glaucoma and diabetic retinopathy…
Maternal use of antiglaucoma medications is associated with increased risk of low birth weight
Understanding the Impact of Eye Drop Medications on Pregnancy Outcomes
This meta-analysis of 3,713 cases evaluated the impact of maternal antiglaucoma medication use on pregnancy outcomes. The analysis found an …
New data looks at how glaucoma eye drops affect babies. Mothers need clear information to balance their eye health and pregnancy.
Peripheral visual field loss correlates with poorer balance performance and sensory strategies in patients with glaucoma
Peripheral Vision Loss Linked to Poorer Balance in Glaucoma Patients
This systematic review and meta-analysis of 2456 participants found that individuals with peripheral visual field loss (PVFL) exhibit worse …
People with limited peripheral vision, such as those with glaucoma, may experience significant balance issues due to changes in how they pro…
Hydrogels overcome physiological barriers to improve drug delivery and tissue repair in anterior segment diseases
Hydrogels Improve Drug Delivery for Various Eye Conditions
This systematic review evaluates hydrogel platforms including adhesive drops, thermosensitive gels, and drug-eluting lenses compared to conv…
New hydrogel technologies may overcome the limitations of standard eye drops to provide longer-lasting treatment for conditions like glaucom…