Phase 2
Completed N=45
Effect of Miswak and Miswak Extract on Oral Malodor
Oral Malodor · Halitosis
Source: ClinicalTrials.gov NCT02628938 ↗
Enrolled (actual)
45
Serious AEs
—
Results posted
May 2016
Primary outcomePrimary: Organoleptic Scores After the First Use of the Prescribed Method by 15 Minutes (Masking Effect), and After 7 Days of Use (Therapeutic Effect). — 2.10; 1.62; 1.36; 1.10 units on a scale — p=0.299
Summary
The aim of this experiment is to investigate the effect of Miswak on oral malodor and to determine whether this effect -if present- is the result of the mechanical action of Miswak or the chemical effect of its extract
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Organoleptic Scores After the First Use of the Prescribed Method by 15 Minutes (Masking Effect), and After 7 Days of Use (Therapeutic Effect). |
2.10; 1.62; 1.36; 1.10; 0.54; 1.09 | 0.299 |
| SECONDARY Volatile Sulfur Compound Scores After the First Use of the Prescribed Method by 15 Minutes (Masking Effect), and After 7 Days of Use (Therapeutic Effect) |
4.00; 3.38; 4.09; 3.80; 3.23; 4.00 | 0.496 |
| SECONDARY Self-assessment of Mouth Odor After 7 Days of Use |
2.00; 1.92; 2.18 | 0.008 sig |
Eligibility Criteria
Inclusion Criteria
- the participants should report that they suffered from bad oral malodor
- organoleptic score of 2 or above
Exclusion Criteria
- smoking
- current systemic diseases or medical treatment
- active caries or any faulty restorations
- acute sinusitis or oro-pharyngeal infection
- chronic periodontitis
- pregnancy
- breast feeding
- eating very spicy food
- use of antibiotic during the last two months before the start of the study
Data sourced from ClinicalTrials.gov (NCT02628938). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.