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N/A N=52 Randomized Double-blind Prevention

Does Fluid Replacement From Preoperative NPO Status Improve Postoperative Recovery

Osteoarthritis

Enrolled (actual)
52
Serious AEs
0.0%
Results posted
Oct 2020
Primary outcome: Primary: Number of Participants With Postoperative Complications — 0; 1; 0; 0 participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Lactated Ringer (Drug); Placebo (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
West Virginia University
Primary completion
Oct 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants With Postoperative Complications
0; 1; 0; 0; 0; 0
SECONDARY
90 Day Readmission Count
0; 1; 20; 18
SECONDARY
Duration of Hospital Stay (Hours)
53.86; 36.13
SECONDARY
Duration of Surgery
122.68; 126.3
SECONDARY
Emesis Episodes
0.26; 0.11
SECONDARY
Volume of Fluid Administred
1635; 1518

Summary

The investigators are testing the hypothesis that administering 2L of body temperature warmed lactated ringer's intravenously prior to surgery can optimize the postoperative and recovery of patients undergoing total hip and total knee arthroplasty.

Eligibility Criteria

Inclusion Criteria

  • All patients >= 18 years of age, undergoing a total primary knee or hip arthroplasty

Exclusion Criteria

  • Patients weighing less than 80 kg.
  • Patients undergoing irrigation and debridement, explantation, or revision will not be eligible.
  • history of kidney disease, congestive heart failure, pulmonary edema, cirrhosis of the liver, or history of systemic fluid overloard will be excluded from the study.
  • No one will be excluded based on gender, ethnicity or race.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02638623). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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