N/A
N=15
Right Ventricular Function and Exercise Capacity in Patients With Continuous-flow Left Ventricular Assist Devices
Heart Failure
Bottom Line
View on ClinicalTrials.gov: NCT02658136 ↗Enrolled (actual)
15
Serious AEs
0.0%
Results posted
Jun 2022
Primary outcome: Primary: Peak Oxygen Uptake — 15 ml/kg/min
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Cardiac Computed tomography (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Finn Gustafsson
- Primary completion
- Aug 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Peak Oxygen Uptake |
15 | — |
| SECONDARY Right Ventricular Function (RVEF) During Exercise |
37 | — |
Summary
Exercise capacity in continous-flow left ventricular assist device (CF-LVAD) patients remains severely reduced post-implant. While the effect of right ventricular (RV) failure early after pump implantation, and its effect on outcome has been extensively studied, the effects of late RV failure on exercise capacity and quality of life (QOL) has been sparsely described. Thus the purpose of this study is to examine RV function and the association to exercise capacity in CF-LVAD patients.
Eligibility Criteria
Inclusion Criteria
- Outpatients from Department of Cardiology, Rigshospitalet, Denmark.
- Age ≥ 18 years.
- Ischemic or non-ischemic cardiomyopathy.
- Signed informed consent.
Exclusion Criteria
- Unstable patients with the need for intravenous inotropic therapy.
- CF-LVAD implantation less than one month ago.
- eGFR < 45 ml/min.
- Contrast allergy.
Data sourced from ClinicalTrials.gov (NCT02658136). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.